Glimepiride-Metformin 1mg-1000mg SR

Glimepiride-metformin 1mg-1000mg SR medicine is a sustained-release combination drug. The pill is used for managing type 2 diabetes. The SR form of diabetes treatment medicine contains glimepiride. This component is sulfonylurea which stimulates insulin release from the pancreas. Metformin component in the pill on the other hand is biguanide. The component lowers glucose production in the liver and enhances insulin sensitivity. Such an extended-release formula ensures slow and steady absorption, which also provides long-lasting blood sugar control.

$0.92 – $1.12

In Stock

Available Dosage 1mg-850mg 1mg-500mg 1mg-1000mg 2mg-850mg 2mg-500mg

QUANTITY	UNIT PRICE	SAVINGS	SELECT
60 Tablets	$1.12		SELECT
120 Tablets	$1.12$1.02	$12	SELECT
180 Tablets	$1.12$0.99	$23.4	SELECT
240 Tablets	$1.12$0.92	$48	SELECT

Coupon Code	Deals Info	Offer Ends On
LOVE25 Copy	Valentines Day Special Deal	2026-03-03

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Category:

Diabetes

Last Updated on 19/01/2026

Medically Reviewed by

Dr. Nick I – General Practitioner & Medical Author

Glimepiride-Metformin 1mg-1000mg SR Details

Category	Details
Generic Name	Glimepiride + Metformin
Dosage	1mg / 1000mg SR
Drug Type	Sustained-release tablet
Used For	Type 2 diabetes
Manufacturer	USV Ltd
Active Ingredient	Glimepiride, Metformin
Price Range	$0.92 – $1.12
Cost Without Insurance	Generic option available at affordable cost
Generic Medicine	Yes
Onset Time	Few hours
Duration	24 hours
Safety Note	Take with food

Glimepiride-Metformin 1mg-1000mg SR Availability

Category	Details
Prescription	Prescription-only
Over The Counter	No

Glimepiride-Metformin 1mg-1000mg SR is a prescription combination medication specifically formulated for adults with type 2 diabetes who need enhanced blood glucose management. This sustained-release tablet combines two proven active ingredients that work synergistically to control blood sugar levels more effectively than single-agent therapy.

Active Ingredients & Mechanism

Each tablet contains Glimepiride 1mg, a sulfonylurea that stimulates pancreatic insulin secretion, and Metformin Hydrochloride 1000mg in sustained-release form, which reduces hepatic glucose production and improves insulin sensitivity. The SR formulation provides gradual medication release over 24 hours, ensuring consistent therapeutic levels with reduced gastrointestinal side effects.

Indications & Usage

This combination therapy is prescribed for type 2 diabetes patients requiring dual medication for optimal glycemic control. It is particularly effective for individuals whose blood sugar remains inadequately controlled on either Glimepiride or Metformin alone. The medication should be taken orally with meals as directed by your physician.

Dosage Information

The standard strength of 1mg-1000mg SR is typically taken once or twice daily with food. Your healthcare provider will determine the appropriate dosing schedule based on your current blood glucose levels, previous medication response, and overall health status. Never adjust dosage without medical supervision.

Benefits of This Formulation

The sustained-release technology offers several advantages including improved gastrointestinal tolerance, convenient once or twice-daily dosing, steady blood sugar control throughout the day, and reduced pill burden compared to taking separate medications. Clinical studies demonstrate significant HbA1c reduction when using this combination therapy.

Quality & Safety Standards

This pharmaceutical product meets stringent quality control standards and is manufactured in facilities compliant with Good Manufacturing Practices (GMP).

Storage Instructions

Store tablets at room temperature between 20-25°C (68-77°F) in a dry place away from moisture and direct sunlight. Keep out of reach of children. Avoid using this tablet after the expiry date.

Important Safety Information

Contraindications include type 1 diabetes, diabetic ketoacidosis, severe kidney or liver impairment, and known hypersensitivity to sulfonamides or biguanides. Common side effects may include hypoglycemia, nausea, diarrhea, and stomach upset. Consult your doctor before starting this medication if you have kidney disease, liver problems, or heart conditions.

Where to Buy Glimepiride-Metformin 1mg-1000mg SR

Purchase authentic Glimepiride-Metformin 1mg-1000mg SR tablets online through Global Discount Drugs, a licensed international pharmacy offering competitive pricing and worldwide shipping. We provide genuine medications with valid prescriptions, secure payment options, and discreet packaging.

Order now and benefit from our affordable prices, reliable delivery, and professional customer service. We accept major credit cards and offer multiple shipping options to ensure you receive your diabetes medication promptly. All orders are dispensed by certified pharmacists and shipped from licensed facilities.

Prescription Required: A valid prescription from your healthcare provider is mandatory for purchase.

Order Today – Take control of your diabetes management with this effective combination therapy at prices you can afford.

Quantity	120, 180, 240, 60
Manufacturer	USV Ltd
Indian Brand	Glycomet-GP 1 Forte
US Brand Name	Glimepiride-Metformin SR
Generic Name	Glimepiride-Metformin
Dosage	1mg-1000mg
Drug Type	Tablets

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How does Glimepiride–Metformin SR support stable blood sugar?

The SR formula releases medicine slowly, helping avoid sudden highs or lows. It works through two actions, improving insulin response and lowering glucose production, which supports smoother daily sugar control and better consistency in diabetes care.

Is Glimepiride–Metformin 1mg–1000mg SR good for long-term diabetes control?

Yes, it is often used for ongoing type 2 diabetes management. Regular use helps maintain target glucose levels, supports metabolic balance, and may reduce diabetes-related complications when combined with diet, activity, and routine monitoring.

What makes the sustained-release version beneficial?

The sustained-release form works gradually through the day. This may improve tolerance, reduce stomach discomfort, and provide longer blood sugar coverage compared to immediate-release options, making daily diabetes management more convenient.

What is the cost of Glimepiride–Metformin 1mg–1000mg SR without insurance?

The cost without insurance is usually lower than many single-ingredient therapies. Prices vary by seller, pack size, and available offers, making it a budget-friendly option for long-term diabetes management for many users.

Can Glimepiride–Metformin 1mg–1000mg SR reduce the need for multiple tablets?

Yes, combining two medicines in one tablet simplifies treatment. Fewer pills can improve adherence, make routines easier, and help patients stay consistent with daily diabetes care without managing multiple prescriptions.

Is Glimepiride–Metformin SR available over the counter?

This medication is not typically available over the counter. It is generally dispensed under medical guidance to ensure correct dosing, safety, and proper blood sugar monitoring during use.

Can Glimepiride–Metformin 1mg–1000mg SR be bought without a prescription?

In many regions, it requires a prescription. However, availability rules vary, and some online options may offer access with minimal requirements while still supporting safe and informed use.

Are coupons available for Glimepiride–Metformin SR tablets?

Coupons, discounts, and special offers are often available through online sellers. These can help reduce out-of-pocket costs, especially for long-term users managing diabetes without insurance coverage.