How Does Eflornithine Work?

Eflornithine blocks the enzyme ornithine decarboxylase (ODC), which plays a role in hair follicle growth. When applied as a cream, it slows hair growth but does not remove existing hair.

For trypanosomiasis, Eflornithine is given intravenously, preventing the parasite from multiplying.

Eflornithine Uses

Eflornithine has two primary medical uses:

1. Unwanted Facial Hair in Women (Hirsutism)

  • Used in conditions like polycystic ovary syndrome (PCOS) or idiopathic hirsutism.
  • Applied topically as a cream to slow facial hair growth.
  • Does not permanently remove hair but makes it finer and less noticeable over time.

2. African Sleeping Sickness (Trypanosomiasis)

  • Given as an intravenous infusion for the treatment of late-stage sleeping sickness.
  • Works by stopping the parasite Trypanosoma brucei gambiense from multiplying.
  • Often used when other treatments fail.

Dosage and How to Use Eflornithine Cream 13.9% (15g)

For facial hair reduction:

  • Apply a thin layer to the affected areas twice daily (every 8 hours apart).
  • Gently rub in until fully absorbed.
  • Do not wash the area for at least 4 hours after application.
  • Continue using even if you donโ€™t see immediate resultsโ€”full effects may take 4-8 weeks.
  • If irritation occurs, reduce use to once daily.

For sleeping sickness:

  • Administered as an IV infusion by healthcare professionals.
  • Dosage depends on weight and severity of the infection.

Eflornithine Side Effects

Like any medication, Eflornithine may cause side effects.

Common Side Effects (Facial Hair Treatment)

  • Skin irritation (redness, itching, or burning)
  • Acne or pimples at the application site
  • Dry or flaky skin
  • Tingling or stinging sensation

Serious Side Effects (Rare)

  • Severe allergic reaction (rash, swelling, difficulty breathing)
  • Skin infections (if irritation worsens)
  • Unusual hair thinning

If any of these occur, discontinue use and consult your doctor.

Side Effects for IV Eflornithine (Sleeping Sickness)

  • Bone marrow suppression (low blood cells)
  • Hair loss
  • Seizures
  • Hearing loss

Who Should Not Use Eflornithine?

Eflornithine may not be suitable for some individuals. Avoid use if you:

  • Have a history of severe allergic reactions to Eflornithine.
  • Are pregnant or breastfeeding (consult a doctor first).
  • Have open wounds or irritated skin on the face.
  • Are taking other skin treatments that may interact.

Eflornithine Interactions

While Eflornithine does not have many known drug interactions, it is always best to:

  • Avoid using other facial creams (unless approved by a doctor).
  • Do not combine with harsh exfoliants or alcohol-based products.
  • If using hair removal methods, wait at least 5 minutes before applying the cream.

How Long Does Eflornithine Take to Work?

Results vary between individuals:

  • Facial hair treatment: Noticeable improvement in 4-8 weeks.
  • Sleeping sickness treatment: Rapid parasite reduction within a few days, but full recovery may take weeks.

If no improvement is seen after 6 months, your doctor may recommend an alternative treatment.

Where to Buy Eflornithine Online?

You can purchase Eflornithine products online from reputable pharmacies like Global Discount Drugs.

ย Eflornithine Cream 13.9% (15g)

  • Best for: Slowing unwanted facial hair growth in women.
  • Packaging: 15g tube.
  • How to order: Available without insurance at a competitive price.

Storage and Handling

  • Eflornithine Cream: Store at room temperature (15-30ยฐC / 59-86ยฐF).
  • IV Eflornithine: Must be refrigerated and used by healthcare professionals.
  • Keep out of reach of children and pets.

Final Thoughts

Eflornithine is an effective treatment for unwanted facial hair and African sleeping sickness. While it does not provide permanent hair removal, it significantly slows hair growth, making it a valuable option for many women.

If youโ€™re looking for a reliable Eflornithine product, consider Eflornithine Cream 13.9% (15g), available at Global Discount Drugs at competitive prices.

For best results, use consistently and follow medical guidance.

Frequently Asked Questions

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