What is Ketoconazole?

Ketoconazole is a prescription antifungal medication available as a tablet, cream, or shampoo. It is widely used to treat various fungal infections affecting the skin, scalp, and internal organs. This effective oral and topical antifungal works by targeting the fungus responsible for infections, helping restore healthy skin and prevent the spread of fungal diseases.

Ketoconazole used for

Ketoconazole is prescribed for:

  • Treating skin fungal infections such as ringworm, athlete’s foot, and jock itch

  • Managing seborrheic dermatitis of the scalp with medicated shampoo

  • Treating systemic fungal infections under medical supervision

  • Addressing yeast infections caused by Candida species

  • Preventing recurrence of chronic fungal infections

Chemical composition

The active ingredient in Ketoconazole products is Ketoconazole, which belongs to the imidazole class of antifungals. Tablets may contain inactive ingredients like lactose and magnesium stearate, while creams and shampoos include agents to stabilize the formulation and improve absorption.

Ketoconazole Mechanism

Ketoconazole works by inhibiting fungal cell membrane synthesis, specifically blocking ergosterol production, an essential component of fungal cells. Without ergosterol, fungal cells become weak, unable to grow, and eventually die. This dual action helps treat both topical and systemic fungal infections effectively.

How does it help to recover from fungal infections?

Ketoconazole reduces fungal growth and infection, relieving symptoms like itching, redness, scaling, and hair loss. In systemic infections, it helps clear the fungus from internal organs, improving overall health. Regular use under medical guidance ensures effective recovery and reduces the risk of recurrence.

What are the other Benefits?

  • Can be used in combination with other antifungals for severe infections

  • Helps restore skin and scalp health quickly

  • Prevents secondary bacterial infections caused by scratching or irritation

  • Supports long-term management of chronic fungal conditions

  • Suitable for both adults and children in recommended doses


Dosages

Available strengths or dosage

Ketoconazole is available in multiple forms and strengths:

  • Tablets: 200 mg and 400 mg

  • Creams: 2% strength

  • Shampoos: 1% and 2% concentrations

Dosage depends on the type of infection, severity, and patient age. Doctors may adjust the dose based on treatment response.

How and when to take it

  • Oral tablets: Take once or twice daily with or without food, as prescribed

  • Cream: Apply to the affected area 1–2 times daily for the recommended duration

  • Shampoo: Use 2–3 times per week, leaving it on the scalp for 3–5 minutes before rinsing

  • Complete the full course even if symptoms improve early to prevent recurrence

Overdose caution

Overdose of Ketoconazole tablets may cause nausea, vomiting, liver toxicity, or dizziness. Seek medical attention immediately in case of overdose.


Who can use/take Ketoconazole?

Ketoconazole is suitable for:

  • Adults and children diagnosed with fungal infections

  • Patients requiring topical or systemic antifungal therapy

It may not be suitable for:

  • People with liver disease or known allergies to Ketoconazole

  • Pregnant or breastfeeding women unless specifically advised by a doctor

  • Patients taking medications that may interact with Ketoconazole


Side Effects & Precautions

What are the side effects?

Common side effects include:

  • Mild nausea or stomach upset (oral tablets)

  • Itching, redness, or irritation at the site of cream application

  • Dryness or scalp irritation with shampoo

Serious side effects (rare):

  • Liver damage or jaundice

  • Severe allergic reactions

  • Hormonal changes in long-term use (oral tablets)

What are the Precautions to avoid side effects?

  • Take Ketoconazole exactly as prescribed

  • Avoid alcohol and hepatotoxic drugs during oral therapy

  • Perform liver function tests for prolonged oral use

  • Do not apply cream to broken or open skin

  • Use sunscreen and avoid excessive sunlight when using topical products


Always consult your doctor before starting a dose. If prescribed, you can order Ketoconazole tablets, creams, or shampoo online from trusted pharmacy sources for safe and timely delivery, ensuring effective treatment of fungal infections and healthy skin and scalp.

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