Penicillamine 250mg

Penicillamine 250mg Uses

Penicillamine 250mg is prescribed to:

• Treat Wilson’s disease by reducing excess copper levels in the body.
• Manage rheumatoid arthritis symptoms, such as pain, stiffness, and swelling.
• Prevent and treat kidney stones in patients with cystinuria.

How Does Penicillamine 250mg Work

• In Wilson’s Disease: Penicillamine binds to excess copper in the body, forming a complex that is excreted through urine, preventing copper buildup in organs.
• In Rheumatoid Arthritis: It suppresses the immune system’s overactive response, reducing joint inflammation and slowing disease progression.
• In Cystinuria: It binds to cystine in the urine, forming a soluble compound that prevents stone formation.

How to Use Penicillamine 250mg

• Take Penicillamine 250mg as prescribed by your healthcare provider, usually 1–4 times daily.
• Take the tablet on an empty stomach, 1 hour before or 2 hours after meals.
• Swallow the tablet whole with water.
• Avoid taking the tablet with milk, antacids, or iron supplements, as they can reduce absorption.
• Follow your doctor’s instructions for regular monitoring of blood and urine tests.

Side Effects

Common side effects may include:

• Nausea or vomiting
• Loss of appetite
• Stomach pain
• Diarrhea

Rare but serious side effects include:

• Severe allergic reactions, such as rash, swelling, or difficulty breathing
• Bone marrow suppression, leading to low blood cell counts
• Kidney issues, such as protein in the urine
• Severe skin reactions, including blistering or peeling

Drug Interactions

Penicillamine 250mg may interact with:

• Iron supplements, antacids, and multivitamins containing minerals, reducing its absorption.
• Medications that suppress the immune system, increasing the risk of infections.
• Nonsteroidal anti-inflammatory drugs (NSAIDs), which may increase the risk of kidney problems.

Food Interactions

• Avoid taking Penicillamine with milk or dairy products, as they can interfere with its absorption.
• Maintain a balanced diet as recommended by your healthcare provider, especially in Wilson’s disease.

Penicillamine 250mg Contraindications

This medication is not suitable for:

• Individuals allergic to Penicillamine or its components.
• Patients with a history of aplastic anemia or agranulocytosis.
• Individuals with severe kidney impairment without proper medical supervision.

Precautions and Warnings

• Inform your doctor if you have a history of blood disorders, kidney problems, or lupus.
• Regular monitoring of blood counts, liver function, and urine tests is essential during treatment.
• Pregnant or breastfeeding women should consult their doctor before using Penicillamine.
• Use caution in children, as they may be more sensitive to the effects of the medication.

Storage

• Store Penicillamine 250mg tablets at room temperature, away from moisture, heat, and direct sunlight.
• Keep the tablets in their original packaging and out of reach of children and pets.
• Dispose of unused or expired tablets responsibly, following local disposal guidelines.

Safety Information

• Use Penicillamine 250mg only as directed by your healthcare provider.
• Do not skip doses or stop taking the medication without consulting your doctor.
• Report any unusual symptoms, such as severe skin reactions or signs of infection, to your doctor immediately.