Tofacitinib 5mg

Tofacitinib 5mg Uses

Tofacitinib 5mg is used to treat:

• Rheumatoid Arthritis (RA): Reduces joint pain, swelling, and stiffness in adults with moderate to severe RA.
• Psoriatic Arthritis (PsA): Manages symptoms in adults who do not respond to conventional treatments.
• Ulcerative Colitis (UC): Helps achieve and maintain remission of moderate to severe UC.

This medication is typically prescribed for individuals who have not responded adequately to other therapies.

How Does Tofacitinib 5mg Work?

Tofacitinib is a Janus kinase (JAK) inhibitor that works by blocking specific enzymes involved in the immune system’s inflammatory response. By inhibiting these pathways, Tofacitinib reduces inflammation, prevents joint damage in arthritis, and helps control symptoms of ulcerative colitis. Its targeted action makes it a highly effective option for autoimmune disease management.

How to Use Tofacitinib 5mg

• Take one tablet orally, as prescribed by your doctor, usually once or twice daily.
• Swallow the tablet whole with water, with or without food.
• Follow the prescribed dosing schedule carefully.
• Do not crush, chew, or break the tablet.

Always consult your doctor for personalized dosing instructions based on your condition.

Side Effects

Common side effects may include:

• Headache
• Nausea
• Diarrhea
• Increased blood pressure
• Upper respiratory tract infections

Rare but serious side effects include blood clots, liver enzyme abnormalities, or a higher risk of serious infections. Contact your healthcare provider if you experience severe or persistent symptoms.

Drug Interactions

Avoid taking Tofacitinib with:

• Strong CYP3A4 inhibitors (e.g., ketoconazole)
• Strong CYP3A4 inducers (e.g., rifampin)
• Immunosuppressants (e.g., cyclosporine)
• Other biologic therapies

These combinations may increase the risk of side effects or reduce the effectiveness of Tofacitinib. Inform your doctor about any other medications or supplements you are taking.

Food Interactions

Tofacitinib can be taken with or without food. However, avoid excessive alcohol consumption as it may increase the risk of liver damage or other side effects.

Contraindications

Do not use this medication if you:

• Are allergic to Tofacitinib or any of its components.
• Have active infections, such as tuberculosis.
• Have severe liver or kidney impairment.
• Are taking other JAK inhibitors or biologic therapies.

Consult your doctor to determine if Tofacitinib 5mg is suitable for you.

Precautions and Warnings

Before using Tofacitinib, inform your doctor if you:

• Have a history of infections or conditions that increase the risk of infections.
• Have a history of blood clots, cardiovascular disease, or high cholesterol.
• Are pregnant, planning to become pregnant, or breastfeeding.
• Have any underlying health conditions, such as liver or kidney problems.

Regular monitoring of blood counts, liver function, and lipid levels is recommended during treatment.

Safety Information

Tofacitinib 5mg is a prescription medication and should only be used under medical supervision. Do not share this medication with others. If you miss a dose, take it as soon as you remember unless it is close to the next scheduled dose. Do not double the dose to catch up. Store the medication securely to prevent misuse.

Storage

Store Tofacitinib 5mg tablets in a cool, dry place, away from direct sunlight and moisture. Keep them out of reach of children and pets. Dispose of expired or unused medication responsibly, following local regulations.