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Colchicine 0.5mg
Colchicine 0.5mg is a medication primarily used for the prevention and treatment of gout attacks and familial Mediterranean fever (FMF). It works by reducing inflammation and lessening the build-up of uric acid crystals that cause pain in the joints and surrounding tissues. This lower dose is often used for ongoing maintenance therapy or as part of a dosage strategy to minimize side effects.
$0.52 – $0.63
Colchicine 0.5mg is a medication primarily used for the prevention and treatment of gout attacks and familial Mediterranean fever (FMF). It works by reducing inflammation and lessening the build-up of uric acid crystals that cause pain in the joints and surrounding tissues. This lower dose is often used for ongoing maintenance therapy or as part of a dosage strategy to minimize side effects.
$0.52 – $0.63
Colchicine 0.5mg Uses
Colchicine 0.5mg is prescribed to:
- Prevent and treat acute gout flare-ups by reducing inflammation and pain.
- Manage symptoms of familial Mediterranean fever, a genetic inflammatory disorder.
- Potentially treat other conditions characterized by inflammation, as prescribed by a healthcare provider.
How Colchicine 0.5mg Works
Colchicine works by inhibiting microtubule formation, which in turn affects the function of the inflammatory cells responsible for the symptoms of gout and FMF. This action helps to prevent the activation, degranulation, and migration of neutrophils, cells that contribute to the inflammatory process and result in intense pain and swelling.
How to Use Colchicine 0.5mg
- Take Colchicine 0.5mg orally with or without food, as directed by your healthcare provider. Taking it with food may reduce stomach upset.
- For gout flares, follow your doctor’s instructions on dosage, which may vary depending on your condition and response to treatment.
- For FMF or regular gout prevention, the medication is typically taken once or twice daily.
- It is crucial to follow your healthcare provider’s instructions carefully to avoid taking too much colchicine, as it can lead to serious side effects.
Side Effects
Common side effects of Colchicine include:
- Nausea
- Diarrhea
- Vomiting
- Abdominal pain
Serious side effects requiring immediate medical attention:
- Muscle pain or weakness
- Numbness or tingling in the fingers or toes
- Unusual bleeding or bruising
- Signs of infection (e.g., fever, chills, sore throat)
- Severe allergic reactions (rash, itching/swelling, severe dizziness, trouble breathing)
Drug Interactions
Colchicine can interact with:
- Other drugs that affect the liver enzymes responsible for metabolizing colchicine, potentially leading to higher levels of colchicine in the blood and increased risk of toxicity.
- Certain cholesterol-lowering drugs (statins), anti-fungal medications, and antibiotics.
- Grapefruit juice and grapefruit products, which can increase colchicine levels and the risk of side effects.
Inform your doctor about all medications and supplements you are taking to manage potential interactions effectively.
Precautions and Warnings
- Kidney/Liver Disease: Patients with kidney or liver problems may need dosage adjustments or monitoring due to increased risk of toxicity.
- Blood Disorders: Colchicine can cause bone marrow depression; regular blood monitoring may be required.
- Pregnancy and Breastfeeding: Consult your healthcare provider for advice if you are pregnant or breastfeeding. Colchicine may not be safe for use during pregnancy or breastfeeding.
Storage
Store Colchicine 0.5mg at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications out of reach of children and pets.
Colchicine 0.5mg is effective for managing and preventing painful episodes associated with gout and FMF. Careful adherence to dosing instructions and awareness of potential side effects are crucial for the safe use of this medication.
| Quantity | 100, 200, 300, 400 |
|---|---|
| Manufacturer | Zydus Cadila |
| Indian Brand | Zycolchin 0.5mg |
| US Brand Name | Colchicine, Lengout |
| Generic Name | Colchicine |
| Dosage | 0.5mg |
| Drug Type | Tablets |
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