Montelukast
Montelukast is a leukotriene receptor antagonist (LTRA) used as a maintenance therapy for asthma, exercise-induced bronchoconstriction, and chronic allergic rhinitis. It works by blocking the action of leukotrienes, inflammatory mediators that cause bronchoconstriction, mucus production, and airway edema. This API is particularly effective in aspirin-sensitive and pediatric asthma. Montelukast provides crucial non-steroidal inflammatory control in respiratory diseases.
What is Montelukast?
Montelukast is a leukotriene receptor blocker used to manage chronic asthma, exercise-induced breathing issues, and allergic rhinitis. It is often provided in tablet, chewable tablet, and granule form for different age groups. By reducing airway inflammation, Montelukast helps patients breathe more comfortably and prevents long-term flare-ups.
Montelukast used for
This medicine is used for:
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Long-term management of asthma
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Prevention of exercise-induced bronchoconstriction
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Relief from seasonal or perennial allergic rhinitis
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Reducing nighttime asthma symptoms in children
It is not meant for emergency asthma attacks.
Chemical composition
Montelukast contains the active ingredient Montelukast Sodium, a selective leukotriene receptor antagonist. Inactive ingredients vary by form but may include mannitol, cellulose, flavoring agents (in chewables), and lactose-free fillers.
Montelukast Mechanism
When allergens or irritants enter the airway, the body releases leukotrienes, chemicals that cause inflammation, tightening of airway muscles, and excess mucus. Montelukast blocks leukotriene receptors, preventing these reactions and helping keep airways open.
How does it help with asthma and allergies?
Montelukast helps maintain steady breathing by reducing airway swelling and preventing sudden tightening. For allergy sufferers, it decreases symptoms like sneezing, nasal congestion, watery eyes, and itching. When taken daily, it lowers the frequency and intensity of asthma attacks and improves overall respiratory comfort.
What are the other benefits?
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Reduces nighttime coughing
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Helps patients who cannot tolerate inhaled corticosteroids
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Improves breathing comfort during physical activity
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Provides once-daily symptom control
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Safe and effective for children when used correctly
Dosages
Available strengths or dosage
Common strengths of Montelukast include:
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10 mg tablets (for adults)
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5 mg chewable tablets (for children 6–14 years)
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4 mg chewable tablets or oral granules (for children 2–5 years)
Your doctor will choose the appropriate strength based on age and condition.
How and when to take it
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Usually taken once daily in the evening for asthma.
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For allergies, it may be taken once daily anytime, based on medical advice.
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Chewable tablets should be fully chewed before swallowing.
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Granules can be mixed with soft food or given directly into the mouth.
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Do not use it for sudden breathing attacks—use rescue inhalers instead.
Overdose caution
Taking too much Montelukast may cause:
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Stomach upset
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Drowsiness
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Headache
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Aggressive behavior (rare)
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Thirst or restlessness
Seek immediate care if overdose is suspected.
Who can use/take Montelukast?
Montelukast may be suitable for:
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Adults and children aged 6 months and older (depending on formulation)
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People with asthma needing long-term control
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Individuals with strong allergy symptoms
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Those with exercise-related breathing problems
People who should not use Montelukast without strict supervision:
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Individuals with mental health concerns
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Those allergic to Montelukast Sodium
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Patients with severe liver disease
Always follow medical direction before starting therapy.
Side Effects & Precautions
What are the side effects?
Common side effects may include:
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Headache
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Stomach discomfort
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Cold-like symptoms
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Ear or sinus pain
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Tiredness
Less common but important effects:
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Mood changes
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Trouble sleeping
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Unusual behavior
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Allergic reactions (rare)
If mood or behavior changes occur, contact your doctor immediately.
What are the precautions to avoid side effects?
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Take exactly as prescribed
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Do not stop medication suddenly for asthma control
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Inform your doctor about any mental health history
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Avoid alcohol if it increases drowsiness
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Keep the medicine out of children’s reach
Proper monitoring helps prevent complications.
Always consult your healthcare provider before starting treatment. If prescribed, you can order Montelukast tablets online safely from trusted pharmacy sources and ensure timely refills to maintain your asthma and allergy management.