Fluticasone Furoate-Umeclidinium-Vilanterol Uses

This inhaler is prescribed to:

  • Manage symptoms of COPD, such as shortness of breath, wheezing, and coughing.
  • Reduce the frequency and severity of COPD exacerbations.
  • Improve overall lung function and quality of life in individuals with COPD.

How Does Fluticasone Furoate-Umeclidinium-Vilanterol Work

  • Fluticasone Furoate: Reduces inflammation in the airways, decreasing swelling and mucus production.
  • Umeclidinium: Relaxes airway muscles by blocking muscarinic receptors, helping to keep airways open.
  • Vilanterol: Stimulates beta-2 receptors in the lungs, relaxing airway muscles and improving airflow.
    This triple-action mechanism provides long-lasting relief from COPD symptoms.

How to Use Fluticasone Furoate-Umeclidinium-Vilanterol

  • Use the inhaler exactly as prescribed by your doctor, typically once daily at the same time each day.
  • Exhale fully, then place the mouthpiece in your mouth and inhale deeply. Hold your breath for a few seconds, then exhale slowly.
  • Rinse your mouth with water after use to reduce the risk of oral thrush caused by the corticosteroid component.
  • Do not exceed the recommended dosage or use it to treat acute bronchospasms.

Side Effects

Common side effects may include:

  • Throat irritation or dryness
  • Hoarseness
  • Coughing
  • Headache
  • Runny or stuffy nose

Rare but serious side effects include:

  • Worsening breathing problems or bronchospasm.
  • Signs of adrenal insufficiency, such as fatigue, nausea, or dizziness.
  • High blood pressure or rapid heartbeat.
  • Allergic reactions, such as rash, swelling, or difficulty breathing.

Drug Interactions

Fluticasone Furoate-Umeclidinium-Vilanterol may interact with:

  • Beta-blockers, which may reduce the effectiveness of Vilanterol.
  • Diuretics, increasing the risk of low potassium levels.
  • Medications that suppress the immune system, such as corticosteroids or immunosuppressants.
  • Other anticholinergic or beta-agonist medications, increasing the risk of side effects.

Food Interactions

  • Avoid grapefruit and grapefruit juice, as they may increase the levels of Fluticasone Furoate and Vilanterol in the blood, leading to potential side effects.

Fluticasone Furoate-Umeclidinium-Vilanterol Contraindications

This medication should not be used by:

  • Individuals allergic to any of its components.
  • Patients with severe milk protein allergy, as the inhaler contains lactose.
  • People experiencing acute respiratory distress or bronchospasms.

Precautions and Warnings

  • Inform your doctor if you have a history of heart disease, high blood pressure, diabetes, glaucoma, or thyroid problems.
  • Long-term use may increase the risk of bone loss (osteoporosis) or cataracts; regular check-ups are advised.
  • Pregnant or breastfeeding women should consult their doctor before using this inhaler.

Storage

  • Store the inhaler at room temperature, away from moisture and heat.
  • Keep the inhaler in its original packaging until ready for use.
  • Keep out of reach of children and pets.

Safety Information

  • Use Fluticasone Furoate-Umeclidinium-Vilanterol only as directed by your healthcare provider.
  • Do not use this medication to treat sudden breathing problems or asthma. Keep a rescue inhaler available for emergencies.
  • Report any unusual symptoms, such as worsening breathing or vision changes, to your doctor immediately.
Quantity 1, 2, 3, 4
Manufacturer Glaxo Smithkline
Indian Brand Trelegy Ellipta Powder For Inhalation
US Brand Name Fluticasone Furoate-Umeclidinium-Vilanterol
Generic Name Fluticasone Furoate-Umeclidinium-Vilanterol
Dosage 100mcg-62.5mcg-25mcg
Drug Type Inhalers
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