What is Letrozol?

Letrozol is a prescription hormone therapy tablet commonly used in the treatment of breast cancer in postmenopausal women. As an aromatase inhibitor, it helps reduce estrogen levels in the body, slowing or stopping the growth of hormone-sensitive cancer cells. Letrozol is an effective medication for improving long-term outcomes and supporting overall cancer management under medical supervision.

Letrozol used for

  • Treating hormone receptor-positive breast cancer in postmenopausal women

  • Reducing the risk of cancer recurrence after surgery or other treatments

  • Preventing cancer progression by lowering estrogen levels

  • Supporting long-term hormone therapy plans

  • Managing metastatic breast cancer in certain cases

Chemical composition

The active ingredient in Letrozol tablets is Letrozol, a non-steroidal aromatase inhibitor.

  • Inactive ingredients include lactose, starch, and magnesium stearate to ensure accurate dosing and stability

  • Formulated as oral tablets for consistent absorption

Letrozol Mechanism

Letrozol works by blocking the enzyme aromatase, which converts androgens into estrogen in the body. By reducing estrogen levels, it deprives hormone-sensitive cancer cells of the growth signal they need, slowing tumor growth and helping prevent disease recurrence.

How does it help to recover from breast cancer?

By lowering estrogen levels, Letrozol reduces the proliferation of hormone-sensitive breast cancer cells. Regular therapy helps shrink tumors, prevent new growth, and decrease the risk of recurrence. Over time, this supports long-term cancer management and improves survival outcomes.

What are the other Benefits?

  • Can be combined with other therapies for enhanced efficacy

  • Helps prevent recurrence of breast cancer after surgery or radiation

  • Supports maintenance of long-term hormone balance

  • Improves prognosis in postmenopausal women with hormone receptor-positive cancer

  • Suitable for patients who can adhere to a daily oral therapy regimen


Dosages

Available strengths or dosage

Letrozol tablets are available in:

  • 2.5 mg oral tablets

  • Dosage may vary based on age, health condition, and concurrent treatments

How and when to take it

  • Take once daily, with or without food, at the same time each day

  • Swallow tablets whole with water

  • Continue therapy as prescribed even if symptoms improve

  • Do not change dosage or stop therapy without consulting your doctor

Overdose caution

Overdose may lead to nausea, vomiting, fatigue, or dizziness. Severe overdose requires immediate medical attention.


Who can use/take Letrozol?

Letrozol is suitable for:

  • Postmenopausal women diagnosed with hormone receptor-positive breast cancer

  • Patients who can adhere to a daily oral therapy schedule

It may not be suitable for:

  • Premenopausal women or individuals allergic to Letrozol or tablet excipients

  • Patients with severe liver impairment without medical supervision

  • Pregnant or breastfeeding women unless prescribed by a doctor


Side Effects & Precautions

What are the side effects?

Common side effects include:

  • Hot flashes or sweating

  • Fatigue and dizziness

  • Joint or muscle pain

  • Nausea or mild gastrointestinal discomfort

Rare but serious side effects:

  • Bone density loss leading to osteoporosis

  • Severe allergic reactions

  • Liver enzyme abnormalities

  • Cardiovascular issues in some cases

What are the Precautions to avoid side effects?

  • Take Letrozol exactly as prescribed

  • Maintain regular bone health monitoring during long-term use

  • Inform your doctor about other medications to prevent interactions

  • Report any severe symptoms, including unusual pain, swelling, or jaundice

  • Avoid sudden discontinuation; follow the full therapy course


Always consult your doctor before starting Letrozol. If prescribed, you can order Letrozol tablets online from trusted pharmacy sources for safe and timely delivery, ensuring effective management of hormone-sensitive breast cancer and supporting long-term health.

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