Capecitabine 500mg

Capecitabine 500mg Tablet Uses

Capecitabine 500mg tablet is prescribed to treat certain types of cancers, such as:

• Breast Cancer: Often used in combination with other chemotherapy drugs for advanced or metastatic breast cancer.
• Colorectal Cancer: Used as adjuvant therapy or in advanced stages.
• Gastric Cancer: Frequently used to manage advanced or recurrent cases.

The medication slows or stops the growth of cancer cells, improving survival rates and quality of life.

How Does Capecitabine 500mg Tablet Work?

Capecitabine 500mg tablet is a prodrug, meaning it becomes active only after being metabolized in the body. It converts into fluorouracil (5-FU) in the tumor cells, disrupting the DNA and RNA synthesis essential for cancer cell growth. This targeted action minimizes damage to healthy cells and enhances the effectiveness of treatment.

How to Use Capecitabine 500mg Tablet ?

1. Dosage: Take Capecitabine 500mg tablet exactly as prescribed by your doctor. It is usually taken twice daily, within 30 minutes after a meal, to reduce the risk of stomach upset.
2. Swallow Whole: Do not crush or chew the tablets. Swallow them with water.
3. Duration: Treatment cycles vary depending on your condition, typically involving two weeks of treatment followed by one week of rest.
4. Follow Your Doctor’s Instructions: Ensure you adhere to the schedule provided by your healthcare provider for the best results.

Side Effects

Common side effects of Capecitabine 500mg tablet may include:

• Nausea or vomiting
• Diarrhea
• Fatigue or weakness
• Hand-foot syndrome (redness, swelling, and pain in the hands and feet)
• Loss of appetite

Severe side effects, such as chest pain, shortness of breath, or severe diarrhea, should be reported to your doctor immediately.

Drug Interactions

Capecitabine 500mg can interact with other medications, potentially increasing the risk of side effects or reducing effectiveness. Inform your doctor about all medications you are taking, including:

• Anticoagulants (e.g., warfarin)
• Phenytoin
• Antacids containing aluminum or magnesium
• Other chemotherapy drugs

Food Interactions

Capecitabine 500mg tablet should be taken with food to reduce gastrointestinal side effects. Avoid alcohol, as it may worsen certain side effects like nausea or stomach upset.

Contraindications

Capecitabine 500mg tablet is contraindicated in individuals who:

• Are allergic to Capecitabine or fluorouracil
• Have severe kidney or liver impairment
• Are pregnant or breastfeeding without medical clearance
• Have a known deficiency of the enzyme DPD (dihydropyrimidine dehydrogenase), which is essential for metabolizing the drug

Precautions and Warnings

• Pregnancy and Breastfeeding: Capecitabine can harm an unborn baby. Avoid use during pregnancy and breastfeeding unless explicitly approved by your doctor.
• Monitoring: Regular blood tests are required to monitor your blood cell counts, liver, and kidney function.
• Elderly Patients: May be more sensitive to side effects, particularly gastrointestinal symptoms.

Storage

Store Capecitabine 500mg tablet at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets. Do not use it after the expiration date.

FAQ’S:

What is capecitabine 500mg used for?

Capecitabine 500mg is a chemotherapy medication used to treat colorectal, breast, and gastric cancers. It works by slowing the growth of cancer cells and is often prescribed alone or with other cancer treatments.

Is capecitabine a strong chemotherapy?

Yes, capecitabine is a strong chemotherapy drug. It is an oral prodrug that converts into fluorouracil (5-FU) in the body, which targets and destroys cancer cells.

What foods should you avoid when taking capecitabine?

Avoid grapefruit, high-fiber foods, and alcohol. These can affect absorption or worsen side effects like nausea and diarrhea. Also, limit processed and fatty foods.

How much does capecitabine 500mg cost?

The cost of capecitabine 500mg varies by location, pharmacy, and insurance. Prices range from $200 to $1,000 for a 60-tablet supply.

What is the average price of capecitabine 500mg?

The average price of capecitabine 500mg is around $300 to $800 for a one-month supply, but costs can differ based on brand, dosage, and pharmacy discounts.