Letrozol 2.5mg

Letrozole 2.5mg Uses

Letrozole 2.5mg is prescribed to:

• Treat hormone receptor-positive breast cancer in postmenopausal women.
• Reduce the risk of breast cancer recurrence after primary treatment, such as surgery or radiation therapy.
• Stimulate ovulation in women with polycystic ovary syndrome (PCOS) or unexplained infertility.

How Does Letrozole 2.5mg Work

Letrozole inhibits the enzyme aromatase, which is responsible for converting androgens into estrogen. By lowering estrogen levels, it reduces the growth stimulus for estrogen-dependent breast cancer cells and increases follicle-stimulating hormone (FSH) levels, supporting ovulation in fertility treatments.

How to Use Letrozole 2.5mg

• Take Letrozole 2.5mg exactly as prescribed by your healthcare provider.
• Swallow the tablet whole with water, with or without food.
• For breast cancer treatment, it is usually taken once daily for an extended period.
• For ovulation induction, it is typically taken on specific days of the menstrual cycle as directed by your doctor.
• Follow your healthcare provider’s instructions closely for dosage and duration.

Side Effects

Common side effects may include:

• Hot flashes
• Fatigue or tiredness
• Nausea
• Joint or muscle pain
• Dizziness

Rare but serious side effects include:

• Severe bone thinning (osteoporosis) with long-term use
• Liver dysfunction, with symptoms like yellowing of the skin or eyes
• Severe allergic reactions, such as rash, swelling, or difficulty breathing
• Blood clots, with symptoms like swelling, pain, or redness in the limbs

Drug Interactions

Letrozole 2.5mg may interact with:

• Hormone replacement therapies, which can counteract the medication’s effects.
• Tamoxifen or other estrogen-containing medications, which may reduce Letrozole’s efficacy.
• Medications metabolized by liver enzymes, such as certain antifungals or anticonvulsants.

Food Interactions

• Letrozole 2.5mg can be taken with or without food.
• Limit alcohol consumption to avoid exacerbating dizziness or fatigue.

Letrozole 2.5mg Contraindications

This medication is not suitable for:

• Individuals allergic to Letrozole or any of its components.
• Pregnant women, as it may cause harm to the fetus.
• Premenopausal women unless used under strict medical supervision for fertility treatment.

Precautions and Warnings

• Inform your doctor if you have a history of osteoporosis, liver disease, or kidney problems.
• Regular monitoring of bone density is recommended for long-term users to prevent osteoporosis.
• Use effective contraception during treatment if there is a risk of pregnancy.
• Avoid driving or operating heavy machinery if you experience dizziness or fatigue.

Storage

• Store Letrozole 2.5mg tablets at room temperature, away from heat, moisture, and direct sunlight.
• Keep the tablets in their original packaging and out of reach of children and pets.
• Dispose of unused or expired tablets responsibly, following local disposal regulations.

Safety Information

• Use Letrozole 2.5mg only as directed by your healthcare provider.
• Do not skip doses or stop taking the medication without consulting your doctor.
• Report any unusual symptoms, such as persistent bone pain, severe fatigue, or yellowing of the skin, to your healthcare provider immediately.