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Everolimus 0.25mg
In StockEverolimus 0.25mg Tablet is a specialized immunosuppressant used at a low dose to prevent organ rejection after transplant and to treat certain types of advanced cancer. It works by inhibiting a protein (mTOR) that drives cell growth and immune response, providing dual action. Everolimus is a critical, advanced therapy for long-term organ and cancer management.
$8.31 – $10.15 per pill
Everolimus 0.25mg is a prescription medication widely used to treat various health conditions, including certain cancers, organ transplant management, and specific non-cancerous tumors. It belongs to the mTOR inhibitor class of drugs, working by blocking proteins that support cell growth and survival, thereby slowing disease progression.
Everolimus 0.25mg Uses
Everolimus 0.25mg is used for multiple purposes across medical specialties. In cancer treatment, it is effective in managing advanced breast cancer, kidney cancer (renal cell carcinoma), and neuroendocrine tumors by inhibiting pathways essential for cancer cell growth. For organ transplantation, it prevents rejection in kidney or liver transplant patients by suppressing the immune system. It is also prescribed for benign tumors associated with tuberous sclerosis complex (TSC), helping to reduce tumor size in organs such as the brain and kidneys. Everolimus must be used under the guidance of a healthcare provider to ensure its benefits are maximized and side effects minimized.
Drug Interactions
Everolimus 0.25mg interacts with several medications, potentially altering its effectiveness or increasing the likelihood of adverse effects. Antifungal drugs such as ketoconazole and voriconazole can raise Everolimus levels in the blood, which may lead to toxicity. Antibiotics like clarithromycin and erythromycin can have a similar effect, necessitating dose adjustments. Antiepileptic medications such as phenytoin and carbamazepine may reduce the drug’s efficacy by speeding up its metabolism. Immunosuppressants, including cyclosporine, can heighten the risk of infection when combined with Everolimus. Blood thinners like warfarin may increase the likelihood of bleeding, requiring careful monitoring. It is important to inform your doctor about all medications, supplements, and herbal remedies you are taking before starting Everolimus.
Food Interactions
Certain foods and beverages can influence the absorption and efficacy of Everolimus 0.25mg. Grapefruit and grapefruit juice are known to inhibit enzymes responsible for breaking down Everolimus, which can lead to elevated blood levels and an increased risk of side effects. Consuming Everolimus with a high-fat meal may delay its absorption, although this does not significantly impact its overall effectiveness. While alcohol does not directly interact with Everolimus, excessive consumption can strain the liver, potentially affecting the drug’s metabolism. To ensure consistent absorption, Everolimus should be taken at the same time each day, either on an empty stomach or consistently with or without food.
Contraindications
Everolimus 0.25mg is not suitable for everyone. Individuals with a known allergy to Everolimus or related drugs, such as sirolimus, should avoid using it. Patients with severe liver impairment may experience heightened toxicity, making the drug unsuitable for their condition. Pregnant or breastfeeding women are advised against using Everolimus, as it may harm the fetus or pass into breast milk. Those with active infections should delay starting Everolimus until the infection is fully resolved. Live vaccines are contraindicated during Everolimus treatment, as the drug suppresses the immune system, reducing the body’s ability to respond effectively to the vaccine.
Precautions and Warnings
Several precautions should be followed when using Everolimus 0.25mg to ensure safety. The drug suppresses the immune system, increasing vulnerability to infections. Regular monitoring and prompt reporting of any symptoms are essential. Everolimus can cause non-infectious pneumonitis, leading to breathing difficulties, which should be addressed immediately. Kidney function may be affected, particularly in transplant patients taking cyclosporine concurrently. Wound healing can be delayed, so patients should inform their healthcare provider about any upcoming surgeries. The medication may raise blood sugar levels, requiring close monitoring in diabetic patients. Women of childbearing age must use effective contraception during treatment and for at least eight weeks after discontinuation to avoid pregnancy-related risks.
Storage
Proper storage of Everolimus 0.25mg ensures its efficacy and safety. The medication should be stored at room temperature, between 20°C and 25°C (68°F to 77°F), and kept away from heat, moisture, and direct sunlight. Always keep the tablets in their original blister pack until ready for use to protect them from moisture. The medication should be stored securely out of reach of children and pets. Unused tablets should not be flushed down the toilet; instead, follow local regulations for proper disposal to prevent environmental contamination. Adhering to these storage guidelines helps maintain the stability and effectiveness of Everolimus.
| Quantity | 10, 20, 30, 40 |
|---|---|
| Manufacturer | Novartis |
| Indian Brand | Certican 0.25mg |
| US Brand Name | Everolimus | Zortress |
| Generic Name | Everolimus |
| Dosage | 0.25mg |
| Drug Type | Tablets |
$42.12 – $51.48 per pill
$8.31 per pill
$2.19 – $2.68 per pill
$24.91 – $30.44 per pill
