Sevelamer Hydrochloride 400mg Uses

Sevelamer Hydrochloride 400mg is prescribed for:

  • Hyperphosphatemia Management: Reduces high phosphate levels in patients with CKD on dialysis.
  • Chronic Kidney Disease (CKD): Helps prevent complications like bone disorders and cardiovascular issues caused by high phosphate levels.
  • Phosphorus Control: Supports maintaining balanced phosphorus levels to improve overall health.

This medication is a crucial component of managing CKD-related hyperphosphatemia.

How Does Sevelamer Hydrochloride 400mg Work?

Sevelamer Hydrochloride works by:

  • Binding Dietary Phosphate: Attaches to phosphate from food in the digestive tract, forming an insoluble complex that is excreted in the stool.
  • Preventing Absorption: Reduces the amount of phosphate absorbed into the bloodstream.
  • Lowering Serum Phosphate Levels: Helps maintain balanced phosphorus levels, minimizing the risk of CKD complications.

This mechanism effectively manages hyperphosphatemia, improving patient outcomes.

How to Use Sevelamer Hydrochloride 400mg

  1. Dosage: Take this as prescribed by your doctor, typically with meals.
  2. Administration: Swallow the tablet whole with water. Do not crush, chew, or split the tablet.
  3. Timing: Take this medication with or immediately after meals to ensure optimal phosphate binding.
  4. Adherence: Follow the prescribed dosage and schedule to achieve the best results.

Side Effects

Common side effects of Sevelamer Hydrochloride 400mg include:

  • Nausea or vomiting
  • Stomach pain or bloating
  • Diarrhea or constipation
  • Indigestion

Rare but serious side effects may include intestinal blockage or severe gastrointestinal discomfort. Contact your doctor immediately if these symptoms occur.

Drug Interactions

Sevelamer Hydrochloride 400mg may interact with other medications. Inform your doctor if you are taking:

  • Medications requiring consistent absorption (e.g., thyroid medications or antibiotics)
  • Calcium, magnesium, or other mineral supplements
  • Medications for heartburn or acid reflux

To avoid potential interactions, take other medications at least 1-2 hours before or after Sevelamer.

Food Interactions

  • Meals: Take Sevelamer Hydrochloride with meals to bind dietary phosphate effectively.
  • Calcium-Rich Foods: Monitor calcium intake as recommended by your doctor to ensure proper balance.

Contraindications

Sevelamer Hydrochloride 400mg is contraindicated in individuals who:

  • Are allergic to Sevelamer or its components.
  • Have bowel obstruction or severe digestive issues.
  • Have low blood phosphate levels (hypophosphatemia).

Precautions and Warnings

  • Pregnancy and Breastfeeding: Consult your doctor before using Sevelamer Hydrochloride if you are pregnant or breastfeeding.
  • Intestinal Conditions: Use with caution if you have a history of intestinal disorders.
  • Mineral Monitoring: Regular monitoring of calcium, phosphate, and vitamin D levels is essential.

Safety Information

  • Monitoring: Regular blood tests are recommended to assess phosphate levels and ensure effective treatment.
  • Medication Compliance: Adhere to the prescribed dosage and schedule for optimal results.
  • Dietary Adjustments: Follow dietary recommendations provided by your healthcare provider to support phosphorus control.

Storage

  • Store Sevelamer Hydrochloride 400mg at room temperature, away from heat, moisture, and direct sunlight.
  • Keep the medication in its original container and tightly closed when not in use.
  • Keep out of reach of children and pets.
Quantity 120, 180, 240, 60
Manufacturer Sun Pharma
Indian Brand Revlamer 400
US Brand Name Renagel, Sevelamer Hydrochloride
Generic Name Sevelamer Hydrochloride
Dosage 400mg
Drug Type Tablets

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Frequently Asked Questions

High phosphate levels can cause severe itching in people with kidney problems. Sevelamer Hydrochloride 400mg helps lower phosphate, which may ease this discomfort. Reduced itching can improve daily comfort, sleep quality, and overall quality of life during long-term kidney treatment.

Sevelamer Hydrochloride 400mg works in the gut and is not absorbed into the bloodstream. This means it can be used long term to manage phosphate safely. Its targeted action helps maintain mineral balance without adding extra strain on the kidneys.

Yes, controlling phosphate with Sevelamer Hydrochloride 400mg may help limit calcium buildup in blood vessels. This supports better cardiovascular health over time. Keeping phosphate in check can lower the risk of vessel stiffness, which is a common concern in chronic kidney disease patients.

The cost of Sevelamer Hydrochloride 400mg without insurance can vary based on brand, strength, and quantity. Generic versions are usually more affordable and help patients manage long-term treatment costs. Buying larger quantities or choosing generic options often lowers the per-tablet price, making phosphate control more budget-friendly for ongoing kidney care.

Sevelamer Hydrochloride 400mg is not typically sold over the counter. It is mainly used for managing phosphate levels in chronic kidney disease, which usually requires medical guidance. Even so, some patients look for easier access options online when continuity of treatment is important, especially for long-term phosphate control needs.

In many cases, Sevelamer Hydrochloride 400mg is prescribed, but some online options allow access without a traditional prescription. This can help patients who already know their dosage and need ongoing supply. Always follow advised dosing, as correct use is key for maintaining balanced phosphate levels and overall kidney health.

Coupons and discount offers for Sevelamer Hydrochloride 400mg may be available and can help reduce out-of-pocket costs. These savings options are useful for long-term therapy, especially for patients without insurance. Using coupons can make regular treatment more affordable while continuing the benefits of phosphate control.

Sevelamer Hydrochloride 400mg can be purchased online from pharmacies that offer kidney care medications at competitive prices. Online buying often provides convenience, discreet delivery, and cost savings. It is a practical option for patients needing regular refills and consistent access to phosphate-lowering treatment.

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