What is Rosuvastatin-Fenofibrate?

Rosuvastatin-Fenofibrate is a combination medicine prescribed to help manage high cholesterol and triglyceride levels in adults who need stronger lipid control. This treatment works by improving overall cholesterol balance and lowering harmful fats in the bloodstream. Doctors often recommend this therapy when lifestyle changes and single-drug treatment are not enough to reduce cardiovascular risk.

Rosuvastatin-Fenofibrate Used For

This combination helps lower LDL cholesterol, total cholesterol, and triglycerides while supporting higher HDL levels. It is typically recommended for individuals with mixed dyslipidemia or those at risk of heart disease requiring combination lipid therapy.

Chemical Composition

Rosuvastatin-Fenofibrate contains:

  • Rosuvastatin – a statin that slows the liver’s cholesterol production.

  • Fenofibrate – a fibrate that reduces triglycerides and improves HDL levels.

Together, they deliver a stronger and more balanced lipid-lowering effect.

Rosuvastatin-Fenofibrate Mechanism

The medication works through dual action:

  • Rosuvastatin blocks an enzyme responsible for cholesterol synthesis.

  • Fenofibrate increases fat metabolism, helping the body break down triglycerides more effectively.

This combined mechanism helps reduce dangerous fats in the blood and supports overall heart health.

How It Helps Manage High Cholesterol and Triglycerides

By addressing both cholesterol and triglycerides, this therapy offers better protection against plaque buildup in arteries. It helps improve blood flow, reduces inflammation linked to fat deposits, and lowers the long-term risk of heart attack, stroke, and other cardiovascular complications.

What Are the Other Benefits?

  • Helps maintain healthier lipid levels

  • More effective than using a statin alone for mixed dyslipidemia

  • Supports better triglyceride control

  • Useful for patients who need aggressive lipid management

  • Helps slow the progression of artery blockage


Dosages

Available Strengths or Dosage

Rosuvastatin-Fenofibrate tablets may be available in several combinations, commonly:

  • Rosuvastatin 5mg / Fenofibrate 160mg

  • Rosuvastatin 10mg / Fenofibrate 160mg

  • Rosuvastatin 20mg / Fenofibrate 160mg

Your doctor will decide the best strength based on health condition and lipid levels.

How and When to Take It

  • Take once daily or as directed.

  • Consume with food to improve absorption.

  • Avoid heavy alcohol intake.

  • Follow a cholesterol-friendly diet and regular exercise routine.

  • Do not crush, break, or chew the tablet.

  • Keep taking the medicine even if you feel well, unless your doctor advises otherwise.

Overdose Caution

Taking too much may cause severe muscle pain, dizziness, liver-related symptoms, or stomach upset.
Contact emergency medical help immediately if an overdose is suspected.


Who Can Use/Take Rosuvastatin-Fenofibrate?

This medicine is suitable for:

  • Adults with mixed lipid disorders

  • Individuals needing stronger triglyceride and cholesterol control

  • Men and women at higher risk of heart disease

Not recommended for:

  • Children or teenagers

  • Pregnant or breastfeeding women

  • Patients with severe liver, kidney, or gallbladder issues

  • People with known statin or fibrate intolerance

Your healthcare provider will review your health history to ensure safe use.


Side Effects & Precautions

What Are the Side Effects?

Common side effects may include:

  • Muscle pain

  • Headache

  • Nausea or stomach upset

  • Back pain

  • Elevated liver enzymes

  • Fatigue

Severe but rare effects:

  • Muscle breakdown (rhabdomyolysis)

  • Liver dysfunction

  • Kidney complications

Seek medical attention if symptoms worsen or persist.

What Are the Precautions to Avoid Side Effects?

  • Avoid combining with other lipid-lowering drugs without medical advice.

  • Limit alcohol consumption to protect the liver.

  • Regular blood tests for liver and kidney function are advised.

  • Stay hydrated and report any unexplained muscle pain.

  • Do not take this medicine during pregnancy or breastfeeding.


Always consult your cardiologist before starting the dose. If prescribed, you can order Rosuvastatin-Fenofibrate tablets online safely from trusted pharmacy sources and ensure timely refills to maintain healthy cholesterol levels.

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