Fenofibrate

Fenofibrate is a fibrate class lipid-regulating agent used primarily to treat severe hypertriglyceridemia and mixed dyslipidemia. It works by acting as an agonist for the peroxisome proliferator-activated receptor alpha (PPAR-α), which enhances the clearance of triglyceride-rich lipoproteins and increases HDL synthesis. This API is essential for reducing the risk of pancreatitis caused by very high triglycerides. Fenofibrate is a key drug in complex lipid management.

$0.59 – $1.21

	Fenofibrate 45mg $0.59 – $0.72	Select options This product has multiple variants. The options may be chosen on the product page
	Fenofibrate 135mg $1.09 – $1.33	Select options This product has multiple variants. The options may be chosen on the product page
	Fenofibrate 145mg $1.01 – $1.24	Select options This product has multiple variants. The options may be chosen on the product page
	Fenofibrate 160mg $0.90 – $1.10	Select options This product has multiple variants. The options may be chosen on the product page
	Fenofibrate 200mg $1.21 – $1.48	Select options This product has multiple variants. The options may be chosen on the product page

What is Fenofibrate?

Fenofibrate is a prescription medicine used to lower high triglycerides and improve cholesterol levels. Many people rely on Fenofibrate tablets to manage lipid disorders and support long-term heart health. It belongs to a group of medicines called fibrates, which help the body break down fats more efficiently. Doctors often prescribe Fenofibrate for people who cannot control their cholesterol with diet alone or need extra support alongside statin therapy.

Fenofibrate used for

Fenofibrate is recommended for managing various cholesterol- and fat-related health concerns, including:

High triglycerides (hypertriglyceridemia)
Mixed dyslipidemia, where multiple cholesterol levels are abnormal
Reducing LDL and increasing HDL levels
Supporting heart health in people with long-term lipid imbalances

It is especially useful for people at higher cardiovascular risk or those whose triglycerides remain high despite lifestyle changes.

Chemical composition

The active ingredient in the medicine is Fenofibrate, a lipid-modifying compound. Inactive ingredients often include lactose monohydrate, crospovidone, magnesium stearate, microcrystalline cellulose, and other stabilizers. These ingredients help the tablet dissolve properly and support consistent absorption in the body.

Fenofibrate Mechanism

Fenofibrate works by activating PPAR-alpha receptors, which play a major role in breaking down fats. Once activated, these receptors increase the breakdown of triglycerides and boost “good” HDL cholesterol. The medicine also reduces the production of harmful fats in the liver. This combined effect helps improve overall lipid balance.

How does it help improve lipid health?

High triglycerides can lead to pancreatitis, plaque buildup, and cardiovascular problems. Fenofibrate helps by lowering harmful triglyceride levels while improving HDL, which protects the heart. Over time, this reduces the risk of artery blockages, improves circulation, and supports long-term metabolic health. Combined with lifestyle changes, it can make a noticeable difference in heart wellness.

What are the other Benefits?

People taking Fenofibrate tablets may experience these additional advantages:

Significant reduction in triglyceride levels
Modest increase in protective HDL cholesterol
Helps reduce fatty buildup in blood vessels
Supports heart and liver health
Useful when statins alone are not enough
Can help reduce inflammation linked to high lipid levels

Dosages

Fenofibrate is generally taken once daily and is available in several strengths depending on patient needs. Dose adjustments depend on cholesterol levels, kidney function, and treatment goals.

Available strengths or dosage

Common strengths include 48 mg, 67 mg, 134 mg, 145 mg, and 200 mg tablets or capsules.
Typical guidance:

Standard adult dose: 145 mg once daily
Lower doses for people with kidney concerns
Taken long-term for consistent lipid control

Your doctor may check lipid levels regularly to ensure the right dosage.

How and when to take it

Take Fenofibrate once daily with food to improve absorption.
Swallow the pill whole; do not crush or chew.
Take it at the same time each day for consistent results.
Follow a balanced diet low in saturated fats while using the medicine.
Do not stop taking it even if you feel better—lipid improvement requires ongoing treatment.

Regular exercise, weight management, and avoiding alcohol can help increase the effectiveness of Fenofibrate therapy.

Overdose caution

Taking more than the prescribed dose may cause stomach pain, muscle weakness, nausea, or unusual tiredness. Severe overdose can affect the liver or muscles. If too much is taken accidentally, seek urgent medical attention.