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Ethambutol 400mg
In StockEthambutol 400mg is a prescription medicine. Ethambutol 400mg is a dosage form of ethambutol, an antitubercular medicine used in combination regimens to treat tuberculosis. It works by inhibiting mycobacterial cell wall formation. The dose is determined by the physician.
Last Updated on 12/02/2026
Dr. Roger H – General Practitioner $0.46 – $0.56 per pill
Ethambutol 400mg Uses
Ethambutol 400mg is prescribed to treat active tuberculosis infections in combination with other anti-TB drugs. It is effective in managing both pulmonary (lung) and extrapulmonary (outside the lungs) TB. Additionally, it is sometimes used in treating non-tuberculous mycobacterial infections.
How Does Ethambutol 400mg Work
Ethambutol interferes with the synthesis of the bacterial cell wall by inhibiting the enzyme arabinosyl transferase. This disruption weakens the cell wall, preventing the bacteria from multiplying and aiding the immune system in fighting the infection.
How to Use Ethambutol 400mg
- Take Ethambutol 400mg exactly as prescribed by your doctor, typically once daily.
- It is best taken on an empty stomach, at least 1 hour before or 2 hours after a meal.
- Swallow the tablet whole with water; do not crush or chew it.
- Ensure you complete the entire course of therapy to avoid developing drug-resistant TB.
Side Effects
Common side effects may include:
- Nausea
- Vomiting
- Loss of appetite
- Headache
- Joint pain
Rare but serious side effects can include:
- Vision changes such as blurred vision, difficulty distinguishing colors, or vision loss (optic neuritis).
- Severe allergic reactions like rash, swelling, or difficulty breathing.
- Liver dysfunction with symptoms like yellowing of the skin or eyes and dark urine.
Drug Interactions
Ethambutol 400mg may interact with:
- Aluminum-based antacids, which can reduce the absorption of Ethambutol.
- Other medications for tuberculosis, requiring dosage adjustments to prevent toxicity.
- Medications affecting liver function, such as certain antifungal drugs or antivirals.
Food Interactions
- Avoid alcohol consumption during treatment, as it may increase the risk of liver damage.
- No specific dietary restrictions, but a balanced diet supports recovery and overall health.
Ethambutol 400mg Contraindications
Ethambutol is contraindicated for patients who:
- Have known hypersensitivity to Ethambutol or its components.
- Are unable to undergo regular vision testing, as the medication can cause visual side effects.
- Have severe kidney impairment without dosage adjustments.
Precautions and Warnings
- Inform your doctor if you have a history of eye disorders, kidney problems, or liver disease.
- Regular vision tests are essential during treatment to detect any changes early.
- Pregnant and breastfeeding women should consult their doctor before starting Ethambutol, as its safety in these populations is not fully established.
Storage
- Store Ethambutol 400mg at room temperature, away from heat and moisture.
- Keep the medication in its original packaging and out of reach of children and pets.
- Do not use expired tablets; discard them as per local disposal guidelines.
Safety Information
- Use Ethambutol only as part of a combination therapy for TB as directed by your doctor.
- Do not skip doses or stop treatment prematurely, as this can lead to drug-resistant TB.
- Report any unusual side effects, especially vision problems or signs of liver dysfunction, to your healthcare provider immediately.
- Store Ethambutol 400mg at room temperature, away from heat and moisture.
- Keep the medication in its original packaging and out of reach of children and pets.
- Do not use expired tablets; discard them as per local disposal guidelines.
Safety Information
- Use Ethambutol only as part of a combination therapy for TB as directed by your doctor.
- Do not skip doses or stop treatment prematurely, as this can lead to drug-resistant TB.
- Report any unusual side effects, especially vision problems or signs of liver dysfunction, to your healthcare provider immediately.
Disclaimer:
This content about Ethambutol 400mg is for informational purposes only and does not replace professional medical advice. Always consult a licensed infectious disease specialist or qualified physician before starting, stopping, or adjusting ethambutol therapy. Tuberculosis treatment requires vision monitoring, individualized dosing, and supervision.
| Quantity | 120, 180, 240, 60 |
|---|---|
| Manufacturer | Lupin Ltd |
| Indian Brand | Combutol 400 |
| US Brand Name | Ethambutol, Myambutol |
| Generic Name | Ethambutol |
| Dosage | 400mg |
| Drug Type | Tablets |
$0.37 per pill
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