Estradiol 0.06% W/W Gel Uses

Estradiol 0.06% W/W Gel is prescribed to:

  • Treat vasomotor symptoms of menopause, such as hot flashes and night sweats.
  • Manage atrophic vaginitis and other symptoms of vaginal dryness or irritation.
  • Support estrogen replacement therapy in postmenopausal women.
  • Prevent osteoporosis in postmenopausal women at risk, as part of a broader treatment plan.

How Does Estradiol 0.06% W/W Gel Work

Estradiol, a form of estrogen, works by supplementing the body’s natural hormone levels, which decrease during menopause. The gel:

  • Delivers estradiol through the skin for systemic absorption.
  • Restores hormonal balance, alleviating menopausal symptoms.
  • Supports bone density maintenance and reduces the risk of osteoporosis.

How to Use Estradiol 0.06% W/W Gel

  • Apply the gel as directed by your healthcare provider, typically once daily.
  • Squeeze the prescribed amount onto clean, dry, and unbroken skin on the arms, shoulders, or thighs.
  • Allow the gel to dry before dressing.
  • Wash your hands thoroughly after application.

Important Notes

  • Avoid applying the gel to the breasts, face, or irritated skin.
  • Do not wash the application site for at least 1 hour after applying the gel.

Side Effects

Common side effects may include:

  • Skin irritation or redness at the application site
  • Breast tenderness or swelling
  • Headache or dizziness
  • Nausea or mild stomach discomfort

Rare but serious side effects include:

  • Blood clots, indicated by swelling or pain in the legs or difficulty breathing
  • Unusual vaginal bleeding
  • Signs of liver dysfunction, such as yellowing of the skin or eyes

Seek immediate medical attention if you experience severe or persistent side effects.

Drug Interactions

Estradiol 0.06% W/W Gel may interact with:

  • Anticoagulants, such as warfarin, which may alter bleeding risk.
  • Medications affecting hormone metabolism, such as certain antifungals or anticonvulsants.
  • Thyroid medications, which may require dose adjustments.

Inform your doctor about all medications, supplements, and herbal products you are using to avoid potential interactions.

Food Interactions

  • There are no significant dietary restrictions, but a balanced diet supports overall health.
  • Maintain adequate calcium and vitamin D intake to support bone health during menopause.

Estradiol 0.06% W/W Gel Contraindications

This medication is not suitable for:

  • Individuals allergic to estradiol or any other components of the formulation.
  • Patients with a history of blood clots, stroke, or heart attack.
  • Women with known or suspected estrogen-dependent cancers.
  • Pregnant women, as it may harm the developing fetus.

Precautions and Warnings

  • Inform your doctor if you have a history of liver disease, high blood pressure, or migraines.
  • Use with caution in women with a history of breast cancer or endometriosis.
  • Regular check-ups, including breast exams and pelvic exams, are essential while using this medication.

Storage

  • Store Estradiol 0.06% W/W Gel at room temperature, away from heat and direct sunlight.
  • Keep the tube tightly closed and out of reach of children and pets.
  • Dispose of unused or expired gel responsibly, following local disposal regulations.

Safety Information

  • Use this medication only as directed by your healthcare provider.
  • Do not discontinue therapy without consulting your doctor.
  • Seek immediate medical attention if you experience symptoms such as chest pain, severe headaches, or unusual vaginal bleeding.
Quantity 12, 3, 6, 9
Manufacturer Abbott
Indian Brand Estrabet 0.06% Gel
US Brand Name Estrogel
Generic Name Estradiol
Dosage 0.06%-80gm
Drug Type Tubes

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Frequently Asked Questions
Individuals with a history of hormone-dependent tumors, liver disease, unexplained vaginal bleeding, or thromboembolic disorders should not use this medication without consulting a healthcare provider
The duration of use depends on individual treatment goals and risks, which should be regularly evaluated by your healthcare provider. Typically, HRT should be used at the lowest effective dose for the shortest duration possible.
Estradiol gel should not be used during pregnancy or while breastfeeding as it can affect the baby. Discuss your options with your healthcare provider.
It is best to allow the gel to fully absorb and dry before applying any lotions, creams, or sunscreen to the same area. Wait at least an hour to ensure that the estradiol has been fully absorbed into the skin.
Estradiol Gel is generally prescribed for women; however, in specific cases, it might be used in men. Always consult a healthcare provider for advice tailored to individual health needs and conditions.
In case Estradiol Gel gets into your eyes, rinse them thoroughly with water and seek medical attention if irritation persists.  
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