Eltrombopag
Eltrombopag is a thrombopoietin receptor agonist used to treat thrombocytopenia (low platelet count) in various conditions. It stimulates the bone marrow to produce more platelets, which are essential for blood clotting. It is specifically used for chronic immune thrombocytopenia (ITP), severe aplastic anemia (SAA), and thrombocytopenia in chronic hepatitis C patients undergoing interferon-based therapy.
What is Eltrombopag?
Eltrombopag is a prescription oral tablet medicine used to increase platelet count in people with certain blood-related conditions. It is commonly recommended when the body cannot produce enough platelets, leading to a higher bleeding risk. This medication helps support platelet growth in a controlled and predictable way. Doctors in the USA and worldwide use it as part of long-term treatment plans for specific low-platelet disorders.
Eltrombopag used for
Eltrombopag tablets are mainly used to treat chronic immune thrombocytopenia (ITP), aplastic anemia, and hepatitis C–related thrombocytopenia. It supports patients whose platelet levels stay low even after other treatments.
Chemical composition
Eltrombopag contains Eltrombopag Olamine as the active chemical component. This compound works on platelet-producing cells in the bone marrow. The tablet also includes stabilizers and binding agents to maintain effectiveness and absorption.
Eltrombopag mechanism
Eltrombopag works by activating the thrombopoietin (TPO) receptor, which encourages the bone marrow to produce more platelets. Instead of supplying artificial platelets, it guides your body to build them naturally, helping maintain safer levels over time.
How it helps improve platelet levels
Low platelet count can cause easy bruising, bleeding gums, nosebleeds, and difficulty healing. Eltrombopag helps improve platelet formation, offering a steady rise that reduces bleeding risks. Many patients notice better stability when the medicine is taken as prescribed.
What are the other benefits?
Along with managing platelet levels, Eltrombopag:
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Reduces the need for platelet transfusions
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Supports immune-related blood disorders
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Helps certain hepatitis C patients receive antiviral treatment safely
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Offers an oral alternative compared to injectable therapies
Dosages
A short and helpful description explaining dosage guidance: Eltrombopag tablets are available in different strengths to match individual medical needs. Your doctor will decide the right amount based on your condition, age, and blood test reports.
Available strengths or dosage
Eltrombopag is commonly available in:
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25 mg tablet
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50 mg tablet
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75 mg tablet
Some patients start with a lower dose and increase based on platelet response. The exact strength may vary depending on whether you are being treated for ITP, aplastic anemia, or hepatitis C–related thrombocytopenia.
How and when to take it
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Take Eltrombopag once daily at the same time.
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Swallow the tablet with water.
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Do not take it with dairy products, calcium-rich foods, or mineral supplements within 2–4 hours, as they block absorption.
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Take it on an empty stomach or as directed by your healthcare provider.
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Never change your dose without medical guidance.
Overdose caution
Taking more Eltrombopag than prescribed can raise platelet levels too high and increase clotting risk. If you take an accidental extra dose, contact your doctor or emergency medical help. Signs of overdose may include unusual headaches, vision changes, or chest discomfort.
Who can use/take Eltrombopag?
Eltrombopag may be suitable for:
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Adults and children (age may vary depending on treatment plan)
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Patients diagnosed with chronic ITP, severe aplastic anemia, or hepatitis-related low platelet count
Tell your doctor if you have:
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Liver problems
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Kidney conditions
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Cataracts
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History of blood clots
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Pregnant or breastfeeding status
This medicine may not be right for everyone, and dosing must be monitored closely.
Side Effects & Precautions
What are the side effects
Common side effects include:
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Headache
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Fatigue
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Nausea
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Muscle pain
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Upper abdominal discomfort
Less common but serious effects:
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Liver function changes
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Blood clots
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Cataract formation
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High platelet count
Report any unusual symptoms to your healthcare provider quickly.
What are the precautions to avoid side effects
To reduce risks:
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Get regular blood tests to check platelet counts
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Avoid taking with calcium-rich meals
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Follow the correct timing of doses
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Inform your doctor about all other medications you use
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Limit alcohol, as it affects the liver
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Stay alert for symptoms like leg swelling, chest pain, or severe headaches
Always consult your doctor before starting a dose. If prescribed, you can order Eltrombopag tablets online safely from trusted pharmacy sources and ensure timely refills to maintain your treatment progress.