Anastrozole

What is Anastrozole?

Anastrozole Tablet is a hormonal medicine used to treat breast cancer in postmenopausal women. It belongs to a class of drugs called aromatase inhibitors, which work by lowering estrogen levels in the body. Since certain types of breast cancer grow in response to estrogen, reducing this hormone helps slow or stop the progression of the disease. Anastrozole tablets are commonly prescribed as part of long-term hormone therapy for early or advanced breast cancer.

Anastrozole Used For

• Treat hormone receptor–positive breast cancer in postmenopausal women

• Reduce the risk of cancer recurrence after surgery or radiation

• Manage advanced or metastatic breast cancer that has spread beyond the breast

• Support preventive therapy in high-risk women to reduce the chance of developing breast cancer

By blocking estrogen production, Anastrozole helps maintain hormonal balance and provides a targeted approach to breast cancer management.

Chemical Composition

Each Anastrozole tablet typically contains 1 mg of the active ingredient Anastrozole, along with inactive ingredients such as lactose, magnesium stearate, sodium starch glycolate, and microcrystalline cellulose. These ingredients ensure tablet stability and effective absorption.

Anastrozole Mechanism

Anastrozole works by inhibiting the aromatase enzyme, which converts androgens (produced by the adrenal glands) into estrogen. By blocking this conversion, it significantly reduces estrogen levels in the bloodstream. As many breast cancer cells rely on estrogen to grow, lowering its levels helps slow tumor growth and may even shrink existing tumors.

How It Helps in Breast Cancer Recovery

By suppressing estrogen production, Anastrozole reduces the stimulation of hormone-dependent cancer cells. This effect helps prevent cancer recurrence and supports recovery after surgical or radiation treatment. For women in long-term remission, Anastrozole also helps maintain low estrogen levels, decreasing the risk of cancer returning in the same or opposite breast.

What Are Other Benefits

• Reduces the risk of breast cancer in women at high risk

• Helps manage estrogen-dependent symptoms in cancer patients

• Offers a non-chemotherapy treatment option with fewer systemic side effects

• Can be used as an adjuvant (supportive) therapy after surgery or radiation

• Improves long-term survival outcomes in postmenopausal breast cancer patients

Dosages

Available Strengths or Dosage

Anastrozole is most commonly available as Anastrozole 1 mg tablet, taken once daily. Your doctor may adjust the duration of treatment depending on your response, typically ranging from 5 to 10 years for hormone-positive breast cancer.

How and When to Take It

• Take one Anastrozole tablet daily at the same time each day.

• It can be taken with or without food, with a glass of water.

• Do not stop or skip doses without medical advice, as continuous use is necessary for effectiveness.

• If you miss a dose, take it as soon as possible unless it’s nearly time for your next dose.

Overdose Caution

Overdosing on Anastrozole may lead to dizziness, nausea, or hormonal imbalance. If accidental ingestion occurs, contact your healthcare provider immediately. Always store the tablets away from children and avoid sharing your medication with others.

Who Can Use/Take Anastrozole

Anastrozole is intended for postmenopausal women diagnosed with hormone receptor–positive breast cancer.
It is not recommended for:

• Pregnant or breastfeeding women

• Premenopausal women (unless under specific medical direction)

• Individuals with severe liver or kidney disease

• Patients allergic to Anastrozole or any of its ingredients

Your doctor may evaluate hormone levels and menopause status before prescribing the medicine.

Side Effects & Precautions

What Are the Side Effects

Common side effects include:

• Hot flashes, sweating, or fatigue

• Joint or muscle pain

• Nausea or upset stomach

• Headache or mild dizziness

• Bone thinning or osteoporosis (with long-term use)

Serious but less common effects include:

• Severe allergic reactions or rash

• Chest pain or swelling in limbs

• Liver function changes or jaundice

What Is the Precaution to Avoid Side Effects

• Get bone density tests before and during treatment, as Anastrozole may cause bone loss.

• Maintain a calcium- and vitamin D-rich diet to protect bone health.

• Avoid alcohol and smoking, as they can worsen bone and cardiovascular effects.

• Inform your doctor about all other medicines or supplements you use.

• Report unusual fatigue, bone pain, or mood changes promptly.

• Regularly monitor cholesterol and liver enzyme levels during prolonged use.

Always consult your oncologist before starting or changing your dose. If prescribed, you can order Anastrozole tablets online safely from trusted pharmacy sources and ensure timely refills to maintain your treatment progress.