Imatinib Mesylate 400mg

Imatinib Mesylate 400mg is a prescription medication primarily used to treat certain types of cancer. It is most commonly prescribed for chronic myeloid leukemia (CML) and gastrointestinal stromal tumors (GIST). This medication works by blocking specific proteins that promote cancer cell growth, helping to slow or stop the progression of the disease. It is also effective in treating other conditions, such as Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). Your doctor may prescribe it for other off-label uses based on your health needs.

How to Take Imatinib Mesylate 400mg

1. Dosage: Always take Imatinib Mesylate 400mg exactly as prescribed by your doctor. The dosage will vary depending on the condition being treated.
2. Administration: Take the tablet with a large glass of water, preferably with a meal to avoid stomach upset.
3. Frequency: Typically, it is taken once daily, but your doctor may adjust the schedule.
4. Important Note: Do not crush or chew the tablet; swallow it whole. If you have trouble swallowing, consult your healthcare provider.

Side Effects of Imatinib Mesylate 400mg

Common side effects include:

• Nausea
• Vomiting
• Diarrhea
• Fatigue
• Swelling in the hands or feet

Serious side effects may occur, such as difficulty breathing, severe skin reactions, or liver damage. If you experience any unusual symptoms, contact your healthcare provider immediately.

Drug Interactions

Imatinib Mesylate 400mg can interact with other medications, leading to reduced effectiveness or increased side effects. Some common drug interactions include:

• Blood thinners: Warfarin may increase the risk of bleeding.
• Antifungal medications: Drugs like ketoconazole can raise Imatinib levels in the blood.
• Certain antibiotics: Such as erythromycin or rifampin, which may alter the drug’s effect.
• Herbal products: St. John’s wort can reduce its effectiveness.

• Pregnancy: Avoid using this medication if you are pregnant or planning to conceive, as it may harm the unborn baby.
• Liver Function: Regular liver tests are necessary as this drug can affect liver health.
• Allergic Reactions: Discontinue use and seek medical attention if you experience symptoms like hives, swelling, or difficulty breathing.
• Fluid Retention: Monitor for signs of swelling or rapid weight gain.

Storage

• Temperature: Store at room temperature, between 68°F to 77°F (20°C to 25°C).
• Location: Keep in a dry place away from direct sunlight and moisture.
• Safety: Ensure it is out of reach of children and pets.