Albendazole Tablet 400mg

Albendazole Tablet 400mg 

Albendazole Tablet is an antiparasitic medicine, used for the treatment of parasitic worm infections. It works by killing the worms that cause infections and stops the infection from spreading.

Albendazole Tablet should be used in the dose and duration as advised by your doctor. Take it with or without food, preferably at a fixed time. Avoid skipping any doses and finish the full course of treatment even if you feel better. Do not take a double dose to make up for a missed dose. Simply take the next dose as planned.

Some people may experience vomiting, dizziness, increased liver enzymes, nausea, and loss of appetite as the side effects of this medicine. Please consult your doctor if these side effects persist for a longer duration. You may be monitored with blood tests and liver function tests throughout your treatment.

Uses of Albendazole Tablet 400mg

• Treatment of Parasitic infections

Benefits of Albendazole Tablet 400mg

In Treatment of Parasitic infections

Albendazole Tablet is an antibiotic medicine that helps treat many parasitic worm infections. It works by killing and stopping the further growth of parasites causing the infection. This medicine usually makes you feel better quite quickly. However, you should continue taking it as long as it is prescribed even when you feel better, to make sure that all parasites are killed and do not become resistant. This medicine is generally safe to use while pregnant or breastfeeding, but you should ask your doctor.

Dosage

Albendazole 400mg is prescribed for various parasitic infections, with dosage depending on the condition being treated. For common infections like ascariasis, hookworm, pinworm, and trichuriasis, a single 400mg dose is usually sufficient for adults and children over 2 years old, while children under 2 years typically receive 200mg as a single dose. More complex infections, such as strongyloidiasis and tapeworm infections, require 400mg once daily for three days. In cases of neurocysticercosis, the dosage is based on body weight, with a maximum of 800mg per day divided into two doses, taken for 8 to 30 days. For hydatid disease, treatment involves 400mg twice daily for 28 days, followed by a 14-day break, repeated for three cycles. Albendazole is best taken with a fatty meal to enhance absorption, and it is essential to complete the full course as prescribed.

Side effects of Albendazole Tablet 400mg

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Bandy

• Vomiting
• Dizziness
• Increased liver enzymes
• Nausea
• Loss of appetite

How to use Albendazole Tablet 400mg

Use it as advised by your doctor or check the label for directions before use. Take this medication by mouth. Chew it completely before swallowing, or as directed by your doctor. Albendazole Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Albendazole Tablet 400mg works 

Albendazole Tablet is an antiparasitic medication. It works by keeping the worms from absorbing sugar (glucose), thereby depleting their energy level. This causes the worms to die and treats your infection.

Mechanism of Action

Albendazole works as a broad-spectrum anthelmintic, disrupting the survival of parasites by inhibiting microtubule formation. It binds to β-tubulin, preventing glucose uptake and energy production in parasitic cells. This leads to the gradual paralysis and death of the parasite, effectively clearing the infection. Albendazole is effective against worms, larvae, and eggs, making it useful for treating a wide range of parasitic infections.

Drug Interactions

Albendazole can interact with other medications, affecting its effectiveness or increasing side effects. CYP3A4 inducers like rifampin, phenytoin, and carbamazepine may reduce its levels, making treatment less effective, while CYP3A4 inhibitors such as cimetidine, ketoconazole, and ritonavir can increase its concentration, raising the risk of side effects. The use of dexamethasone may enhance Albendazole metabolism, requiring dose adjustments. Theophylline levels can be altered, requiring careful monitoring. Additionally, Albendazole may increase the effects of warfarin, leading to a higher risk of bleeding, making frequent INR checks necessary for patients on anticoagulants.

Contraindications

Albendazole 400mg is not recommended during pregnancy, especially in the first trimester, due to potential risks to fetal development. Women should confirm they are not pregnant before starting treatment and use contraception during and for at least one month after therapy. Patients with liver disease should take Albendazole cautiously, as it may cause elevated liver enzymes and require monitoring. Rare cases of bone marrow suppression, including low white blood cell counts (leukopenia), have been reported, making blood count monitoring necessary for long-term use. Individuals with known allergies to Albendazole or other benzimidazole derivatives should avoid the medication.