Amlodipine 10mg Tablet

Amlodipine 10 Tablet belongs to a class of medicines known as calcium channel blockers. It is used to treat high blood pressure (hypertension) and prevent angina (heart-related chest pain). It lowers blood pressure and reduces the heart’s workload, which helps prevent heart attacks and strokes.

Amlodipine 10 Tablet may be prescribed alone or along with other medicines. The dose depends on what you are taking it for and the severity of your condition. You can take it at any time of the day, with or without food, but it is best to take it at about the same time each day. You should take this medicine for as long as it is prescribed for you. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Keeping yourself active with regular exercise, managing your weight, and eating a healthy diet will also help control your blood pressure.

The most common side effects include headache, edema, fatigue, nausea, abdominal pain, and somnolence. Consult your doctor if any of these side effects bother you or do not go away. They may be able to suggest ways to prevent or reduce the side effects. There has been reports of lichenoid keratosis (a benign, inflamed, solitary skin lesion, typically brownish or reddish, found on sun-exposed areas) in some patients taking Amlodipine 10 Tablet, if you experience this, let your doctor know.

Before taking it, let your doctor know if you have any liver, heart, or kidney problems. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. You also need to tell your doctor about all the other medicines you are taking, especially those used to treat high blood pressure or heart conditions. You should have your blood pressure checked regularly to make sure that this medicine is working properly.

Uses of Amlodipine Tablet

  • Prevention of Angina (heart-related chest pain)
  • Treatment of Hypertension (high blood pressure)

Benefits of Amlodipine Tablet

In Prevention of Angina (heart-related chest pain)

Amlodipine 10 Tablet relaxes the blood vessels and improves blood flow around your body. This means that more oxygen gets to your heart and reduces the risk of getting chest pain (angina). This medicine should not be used to treat chest pain which is already happening. It is used to prevent or reduce the frequency of angina attacks. This medicine needs to be taken regularly as prescribed for it to work effectively. So, it is important to keep taking it even if you feel well and have no symptoms.

In Treatment of Hypertension (high blood pressure)

Amlodipine 10 Tablet works by relaxing the blood vessels so that blood can flow more easily around your body. This lowers your blood pressure and reduces your risk of having a stroke, a heart attack, or kidney problems in the future. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well. You should take it regularly as prescribed for this medicine to be most effective, even if you feel better.
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Dosage

The usual recommended dose of Amlodipine 10mg is once daily, with or without food. The exact dosage may vary based on individual conditions:

  • Hypertension (High Blood Pressure): 5mg to 10mg once daily.
  • Chronic Stable or Vasospastic Angina: 5mg to 10mg once daily.
  • Elderly or Patients with Liver Impairment: Lower doses (5mg) may be preferred due to slower metabolism.

Patients should take Amlodipine at the same time each day and should not stop taking it abruptly without medical advice.

Side effects of Amlodipine Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Amlodipine

  • Headache
  • Fatigue
  • Nausea
  • Abdominal pain
  • Sleepiness
  • Edema (swelling)

Mechanism of Action

Amlodipine is a calcium channel blocker (CCB) that works by inhibiting the influx of calcium ions into vascular smooth muscle and cardiac muscle. This leads to:

  • Vasodilation: Relaxes blood vessels, reducing blood pressure and improving oxygen supply to the heart.
  • Reduced Cardiac Workload: Decreases the force required for the heart to pump blood, lowering strain on the heart.
  • Anti-Anginal Effect: By increasing blood flow and reducing oxygen demand, it helps prevent angina attacks.

Amlodipine has a long half-life (30–50 hours), providing sustained 24-hour blood pressure control with once-daily dosing.

Contraindications

Amlodipine 10mg should not be used in certain medical conditions:

  • Severe Hypotension (Low Blood Pressure): Can cause extreme dizziness and fainting.
  • Cardiogenic Shock: Can further reduce heart function and worsen the condition.
  • Severe Aortic Stenosis: May reduce coronary perfusion, leading to serious complications.
  • Heart Failure with Reduced Ejection Fraction: Use with caution as it may worsen heart function.
  • Liver Disease: Dose adjustment may be required due to impaired drug metabolism.
  • Pregnancy & Breastfeeding: Should only be used if the benefits outweigh the risks, as safety is not well established.

How to use Amlodipine Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amlodipine 10 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Amlodipine Tablet works

Amlodipine 10 Tablet is a calcium channel blocker. In high blood pressure, it normalizes the blood pressure by relaxing the blood vessels to reduce the pressure on them, thereby improving the blood flow in the body. In heart-related chest pain (angina), the enhanced blood flow in the body relaxes the heart muscles by reducing the workload on the heart. It also improves the oxygen flow in the body, thereby, preventing any heart-related chest pain.
Quantity 120, 30, 60, 90
Manufacturer Cipla Limited
Indian Brand Amlip 10mg
US Brand Name Amlo, Amlodipine, Amlodipine Besylate, Istin, Norvasc
Generic Name Amlodipine
Dosage 10mg
Drug Type Tablets

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