Mesalamine-Mesalazine 1200mg

Uses of Mesalamine 1200mg

Mesalamine 1200mg is used to treat mild to moderate ulcerative colitis by reducing inflammation and symptoms, maintain remission and prevent flare-ups in ulcerative colitis, manage Crohn’s disease in certain cases as prescribed, and promote healing of the intestinal lining and improve quality of life.

How Does Mesalamine 1200mg Work?

Mesalamine 1200mg works by inhibiting the production of inflammatory chemicals (prostaglandins and leukotrienes) in the intestinal lining. It exerts its effect locally within the colon and rectum, reducing swelling, irritation, and tissue damage caused by inflammation. This action helps alleviate symptoms and prevent disease progression.

How to Use Mesalamine 1200mg

Take Mesalamine 1200mg as directed by your healthcare provider, typically once or twice daily. Swallow the tablet whole with a full glass of water; do not crush, chew, or break it, as this may interfere with the medication’s release mechanism. It can be taken with or without food. If you miss a dose, take it as soon as you remember unless it is close to your next scheduled dose. Do not double the dose to make up for a missed one.

Side Effects

Common side effects of Mesalamine 1200mg include nausea or upset stomach, headache, diarrhea or abdominal discomfort, fatigue or dizziness, and mild skin rash or itching. Rare but serious side effects include severe allergic reactions such as rash, swelling, or difficulty breathing, worsening of colitis symptoms, kidney problems indicated by changes in urination, and unusual bleeding or bruising. Seek immediate medical attention if you experience severe or persistent side effects.

Drug Interactions

Mesalamine 1200mg may interact with other medications, including NSAIDs (e.g., Ibuprofen, Naproxen), which may increase the risk of kidney side effects, anticoagulants (e.g., Warfarin), which may increase the risk of bleeding, and immunosuppressants (e.g., Azathioprine, Mercaptopurine), which may increase the risk of bone marrow suppression. Always inform your healthcare provider about all medications, supplements, and herbal products you are using.

Food Interactions

There are no significant food interactions with Mesalamine 1200mg. Maintain a balanced diet and adequate hydration to support intestinal health during treatment.

Contraindications

Mesalamine 1200mg is contraindicated in individuals with known hypersensitivity to Mesalamine, Salicylates, or any other ingredients in the formulation, severe kidney or liver impairment without appropriate medical guidance, and intestinal obstruction or perforation. Your healthcare provider will assess your medical history to ensure the medication is safe for you.

Precautions and Warnings

Regular monitoring of kidney and liver function is recommended, particularly in individuals with pre-existing conditions. Use with caution in individuals with a history of hypersensitivity to salicylates or sulfasalazine. Consult your healthcare provider immediately if you experience severe abdominal pain, blood in the stool, or signs of worsening symptoms. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding, as Mesalamine should be used with caution during these periods.

Safety Information

Seek immediate medical attention if you experience symptoms of severe allergic reactions, such as rash, swelling, or difficulty breathing, worsening abdominal or rectal pain, or unusual bleeding or bruising. Overdose symptoms may include severe diarrhea, abdominal pain, or confusion. Contact a healthcare provider or poison control center immediately if overdose occurs.

Storage

Store Mesalamine 1200mg tablets at room temperature, between 20–25°C (68–77°F). Keep the medication in a dry place, away from direct sunlight and excessive moisture. Avoid storing it in bathrooms. Ensure the medication is out of reach of children and pets. Dispose of unused or expired tablets responsibly, following local waste disposal guidelines.