Uses of Mesalamine 1000mg Suppositories

Mesalamine 1000mg Suppositories are used to treat mild to moderate ulcerative proctitis, reduce rectal inflammation and associated symptoms, prevent flare-ups of ulcerative colitis, and improve rectal and colonic mucosal healing.

How Does Mesalamine 1000mg Suppositories Work?

Mesalamine works by inhibiting the production of inflammatory chemicals in the lining of the colon and rectum, reducing swelling and irritation. This action helps alleviate symptoms such as bleeding, pain, and diarrhea and promotes healing of the inflamed mucosa.

How to Use Mesalamine 1000mg Suppositories

Wash your hands thoroughly before and after using the suppository.

  • Position: Lie on your side with one leg bent toward your chest for ease of insertion.
  • Insert: Gently insert the suppository into the rectum, pointed end first, ensuring it is fully inserted.
  • Frequency: Use as directed by your healthcare provider, typically once daily at bedtime.
  • Duration: Retain the suppository for as long as possible, preferably overnight, to ensure maximum effectiveness.

If you miss a dose, use it as soon as you remember. If it is close to the next scheduled dose, skip the missed dose. Do not use two doses at the same time.

Side Effects

Common side effects include rectal discomfort or irritation, abdominal pain or cramping, diarrhea, and headache. Rare but serious side effects include severe allergic reactions such as rash, swelling, or difficulty breathing, severe worsening of colitis symptoms, unusual bleeding or bruising, and changes in urine color or quantity (indicative of kidney problems). Seek immediate medical attention if you experience severe or persistent side effects.

Drug Interactions

Mesalamine 1000mg Suppositories may interact with other medications, including NSAIDs (e.g., Ibuprofen, Naproxen), which may increase the risk of kidney side effects, anticoagulants (e.g., Warfarin), which may increase bleeding risk, and immunosuppressants (e.g., Azathioprine, Mercaptopurine), which may increase the risk of bone marrow suppression. Always inform your healthcare provider about all medications, supplements, and herbal products you are using.

Food Interactions

There are no known significant food interactions with Mesalamine suppositories. Maintain a balanced diet and adequate hydration to support overall gastrointestinal health.

Contraindications

Mesalamine 1000mg Suppositories are contraindicated in individuals with known hypersensitivity to Mesalamine, Salicylates, or any other ingredients in the formulation, severe kidney or liver impairment without appropriate medical guidance, and intestinal obstruction or perforation. Your healthcare provider will evaluate your medical history to ensure the medication is safe for you.

Precautions and Warnings

Regular monitoring of kidney and liver function is recommended during treatment, particularly in individuals with pre-existing conditions. Use with caution if you have a history of hypersensitivity to salicylates or sulfasalazine. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding, as Mesalamine should be used with caution during these periods. Consult your healthcare provider if symptoms worsen or do not improve within a few weeks of treatment.

Safety Information

Seek immediate medical attention if you experience symptoms of severe allergic reactions, worsening rectal or abdominal pain, or unusual bleeding or bruising. Overdose symptoms may include severe abdominal pain, diarrhea, or confusion. Contact a healthcare provider or poison control center immediately if overdose occurs.

Storage

Store Mesalamine 1000mg Suppositories at room temperature, between 20–25°C (68–77°F). Keep the medication in a dry place, away from direct sunlight and excessive moisture. Avoid storing it in bathrooms. Ensure the medication is out of reach of children and pets. Dispose of unused or expired suppositories responsibly, following local waste disposal guidelines.

Quantity 105, 140, 35, 70
Manufacturer Sun Pharma
Indian Brand Mesacol 1g Suppository
US Brand Name Apriso, Asacol, Canasa, Lialda, Mesalamine/Mesalazine, Mesasal, Pentasa, Rowasa, Salofalk
Generic Name Mesalamine/Mesalazine
Dosage 1000mg-Supp
Drug Type Suppositories
Be the first to review “Mesalamine-Mesalazine 1000mg Suppositories”

Your email address will not be published. Required fields are marked *


Reviews

There are no reviews yet.

Product was successfully added to your cart!