Valsartan-Hydrochlorothiazide 80mg/12.5mg Uses

Valsartan-Hydrochlorothiazide 80mg/12.5mg is prescribed to:

  • Lower high blood pressure (hypertension) in adults.
  • Reduce the risk of cardiovascular events, including heart attack and stroke.
  • Provide enhanced blood pressure control when monotherapy (single medication) is insufficient.

This combination therapy is particularly beneficial for patients who need additional support to achieve optimal blood pressure control.

How Does Valsartan-Hydrochlorothiazide 80mg/12.5mg Work?

Valsartan-Hydrochlorothiazide 80mg/12.5mg works through the following mechanisms:

  • Valsartan (80mg): Blocks the action of angiotensin II, a hormone that causes blood vessel constriction, leading to relaxed blood vessels and improved blood flow.
  • Hydrochlorothiazide (12.5mg): Increases the excretion of excess sodium and water through urine, reducing fluid retention and lowering blood pressure.

These complementary actions make the medication effective in achieving sustained blood pressure reduction.

How to Use Valsartan-Hydrochlorothiazide 80mg/12.5mg

Follow these instructions for safe and effective use:

  1. Dosage: Take Valsartan-Hydrochlorothiazide 80mg/12.5mg exactly as prescribed by your doctor, typically once daily.
  2. With or Without Food: The tablet can be taken with or without food.
  3. Swallow Whole: Swallow the tablet with a glass of water. Do not crush or chew it.
  4. Timing: Take the medication at the same time each day, preferably in the morning to avoid nighttime urination.
  5. Missed Dose: If you miss a dose, take it as soon as you remember unless it is close to your next dose. Do not double the dose.

Side Effects

Valsartan-Hydrochlorothiazide 80mg/12.5mg is generally well-tolerated, but some individuals may experience side effects. These include:

  • Common Side Effects:
    • Dizziness or lightheadedness, especially when standing
    • Increased urination
    • Nausea or mild stomach discomfort
    • Fatigue
  • Rare Side Effects:
    • Severe allergic reactions, such as rash or swelling
    • High potassium levels, which may cause muscle weakness or irregular heartbeat
    • Dehydration or electrolyte imbalances
    • Kidney or liver function impairment

Seek immediate medical attention if you experience severe side effects, such as chest pain, difficulty breathing, or significant changes in urination.

Drug Interactions

Valsartan-Hydrochlorothiazide 80mg/12.5mg may interact with other medications, potentially altering its effectiveness or increasing the risk of side effects. Common interactions include:

  • Other Diuretics or Antihypertensive Medications: May increase the risk of low blood pressure or electrolyte imbalances.
  • Potassium Supplements or Salt Substitutes: May elevate potassium levels.
  • Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Can reduce the effectiveness of the medication and increase the risk of kidney damage.

Inform your doctor about all medications, supplements, and herbal products you are using before starting this combination therapy.

Food Interactions

Certain dietary habits may influence the effects of Valsartan-Hydrochlorothiazide 80mg/12.5mg:

  • Avoid High-Potassium Foods: Consume potassium-rich foods like bananas and oranges in moderation to prevent elevated potassium levels.
  • Hydration: Drink plenty of water to avoid dehydration, especially during hot weather or physical activity.
  • Limit Salt Intake: A low-sodium diet enhances the medication’s effectiveness.

Follow your doctor’s dietary recommendations for the best results.

Contraindications

Valsartan-Hydrochlorothiazide 80mg/12.5mg is not suitable for everyone. Avoid use if:

  • You are allergic to Valsartan, Hydrochlorothiazide, or any of the components.
  • You are pregnant or planning to become pregnant, as the medication may harm the fetus.
  • You have severe kidney or liver impairment or are unable to produce urine (anuria).

Consult your doctor to ensure this medication is appropriate for your condition.

Precautions and Warnings

To use Valsartan-Hydrochlorothiazide 80mg/12.5mg safely, consider these precautions:

  • Monitor Blood Pressure: Regular monitoring ensures the medication is effectively managing your condition.
  • Pregnancy and Breastfeeding: Avoid use during pregnancy and breastfeeding unless specifically directed by a doctor.
  • Kidney and Electrolyte Levels: Periodic blood tests may be required to monitor kidney function and electrolyte balance.

Discuss any medical conditions or concerns with your healthcare provider before starting this medication.

Storage

Store Valsartan-Hydrochlorothiazide 80mg/12.5mg properly to maintain its effectiveness:

  • Temperature: Keep at room temperature (20–25°C), away from heat and sunlight.
  • Dry Location: Store in a dry place to prevent moisture damage.
  • Child Safety: Ensure the medication is stored out of reach of children and pets.
  • Original Packaging: Retain the tablets in their original container to protect them from environmental exposure.

Dispose of unused or expired medication responsibly.

Safety Information

For safe and effective use of Valsartan-Hydrochlorothiazide 80mg/12.5mg:

  • Follow Directions: Take the medication exactly as prescribed by your doctor.
  • Monitor Side Effects: Report unusual symptoms, such as muscle weakness or persistent dizziness, to your healthcare provider.
  • Avoid Overuse: Taking more than the prescribed dose can increase the risk of side effects.
  • Combine With Healthy Practices: Maintain a heart-healthy lifestyle, including regular exercise, a balanced diet, and stress management, to enhance treatment outcomes.

When used as directed, Valsartan-Hydrochlorothiazide 80mg/12.5mg effectively manages high blood pressure, reducing the risk of cardiovascular complications and improving overall heart health.

Quantity 120, 30, 60, 90
Manufacturer Torrent Pharmaceuticals Ltd
Indian Brand Valzaar-H
US Brand Name Diovan Hct
Generic Name Valsartan-Hydrochlorothiazide
Dosage 80mg-12.5mg
Drug Type Tablets
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