Sirolimus 1mg
Sirolimus 1mg is an immunosuppressive medication used to prevent organ rejection in patients who have undergone kidney transplants. By suppressing the immune system, it helps reduce the body’s natural response to reject the transplanted organ. Sirolimus 1mg is also prescribed for other medical conditions, including certain rare autoimmune and skin disorders.
$7.31 – $8.94
Sirolimus 1mg is an immunosuppressive medication used to prevent organ rejection in patients who have undergone kidney transplants. By suppressing the immune system, it helps reduce the body’s natural response to reject the transplanted organ. Sirolimus 1mg is also prescribed for other medical conditions, including certain rare autoimmune and skin disorders.
Sirolimus 1mg Uses
Sirolimus 1mg is prescribed to:
- Prevent organ rejection in patients who have received a kidney transplant.
- Be used in combination with other immunosuppressants like cyclosporine and corticosteroids.
- Treat certain rare conditions, such as lymphangioleiomyomatosis (LAM), a lung disorder, as directed by a doctor.
How Does Sirolimus 1mg Work
Sirolimus inhibits the activation and proliferation of T-lymphocytes, a type of white blood cell responsible for immune responses. By targeting these cells, Sirolimus prevents the body from attacking the transplanted organ, reducing the risk of organ rejection. It also has antiproliferative properties, which may be beneficial in specific conditions.
How to Use Sirolimus 1mg
- Take Sirolimus 1mg exactly as prescribed by your healthcare provider, typically once daily.
- Swallow the tablet whole with water, with or without food. Maintain a consistent schedule (either always with food or always without food).
- If taken with cyclosporine, administer Sirolimus 4 hours after the cyclosporine dose.
- Do not crush, chew, or break the tablet.
- Regular blood tests are required to monitor drug levels and adjust dosages as needed.
Side Effects
Common side effects may include:
- Stomach pain, diarrhea, or nausea
- Headache or dizziness
- High cholesterol or triglycerides
- Swelling in the hands, feet, or lower legs
Rare but serious side effects include:
- Severe infections due to a weakened immune system
- Delayed wound healing
- Lung problems, such as interstitial lung disease, with symptoms like shortness of breath or coughing
- Liver or kidney dysfunction
Drug Interactions
Sirolimus 1mg may interact with:
- Cyclosporine, which requires specific timing to avoid increased toxicity.
- Antifungal medications, such as ketoconazole, and antibiotics like erythromycin, which may increase Sirolimus levels.
- Anticonvulsants, such as carbamazepine or phenytoin, which may lower its effectiveness.
- Grapefruit or grapefruit juice, which can increase Sirolimus blood levels, leading to toxicity.
Food Interactions
- Avoid grapefruit and grapefruit juice, as they interfere with the metabolism of Sirolimus.
- Maintain a balanced diet to support overall health during treatment.
Sirolimus 1mg Contraindications
This medication is not suitable for:
- Individuals allergic to Sirolimus or any of its components.
- Pregnant or breastfeeding women, as Sirolimus may harm the baby.
- Patients with severe liver dysfunction unless specifically advised by a healthcare provider.
Precautions and Warnings
- Inform your doctor if you have a history of liver or kidney problems, high cholesterol, or infections.
- Avoid live vaccines during treatment, as Sirolimus suppresses the immune system.
- Use effective contraception during treatment and for 12 weeks after stopping Sirolimus, as it may harm an unborn baby.
- Regular monitoring of blood counts, kidney function, and cholesterol levels is essential.
Storage
- Store Sirolimus 1mg tablets at room temperature, away from heat, moisture, and direct light.
- Keep the medication in its original packaging and out of reach of children and pets.
- Dispose of unused or expired tablets responsibly, following local regulations.
Safety Information
- Use Sirolimus 1mg only as prescribed by your healthcare provider.
- Do not alter your dose or stop taking the medication without consulting your doctor.
- Report any unusual symptoms, such as signs of infection, lung problems, or severe allergic reactions, to your healthcare provider immediately.
Quantity | 12, 24, 36, 48 |
---|---|
Manufacturer | Zydus Cadila |
Indian Brand | Siromus 1mg |
US Brand Name | Rapamune, Sirolimus |
Generic Name | Sirolimus |
Dosage | 1mg |
Drug Type | Tablets |
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