Sulfamethoxazole-Trimethoprim 800mg-160mg Uses

This combination antibiotic is prescribed to:

  • Treat urinary tract infections (UTIs), including cystitis and pyelonephritis.
  • Manage respiratory tract infections, such as bronchitis and pneumonia.
  • Address gastrointestinal infections, including traveler’s diarrhea.
  • Treat skin infections caused by susceptible bacteria.
  • Manage specific opportunistic infections, such as Pneumocystis jirovecii pneumonia (PJP).

How Does Sulfamethoxazole-Trimethoprim 800mg-160mg Work

This medication combines two antibiotics:

  • Sulfamethoxazole: Inhibits bacterial production of folic acid, which is essential for bacterial growth.
  • Trimethoprim: Enhances the effect of Sulfamethoxazole by preventing bacterial utilization of folic acid.

Together, they effectively stop the growth and spread of bacteria, clearing the infection.

How to Use Sulfamethoxazole-Trimethoprim 800mg-160mg

  • Take this medication exactly as prescribed by your healthcare provider, usually once or twice daily.
  • Swallow the tablet with a full glass of water to prevent dehydration and kidney issues.
  • Take the medication with or without food, but if stomach upset occurs, take it with food or milk.
  • Complete the full course of treatment, even if you feel better, to ensure the infection is completely eradicated.

Side Effects

Common side effects may include:

  • Nausea or vomiting
  • Diarrhea or loss of appetite
  • Skin rash or itching
  • Dizziness or headache

Rare but serious side effects include:

  • Severe allergic reactions, such as rash, swelling, or difficulty breathing
  • Blood disorders, with symptoms like unusual bruising, bleeding, or fatigue
  • Kidney problems, with symptoms like reduced urination or back pain
  • Severe skin reactions, such as Stevens-Johnson syndrome

Drug Interactions

Sulfamethoxazole-Trimethoprim 800mg-160mg may interact with:

  • Blood thinners, such as warfarin, increasing the risk of bleeding.
  • Diuretics, which may heighten the risk of certain side effects.
  • Medications affecting kidney function, requiring dose adjustments.
  • Methotrexate, increasing its toxicity.

Food Interactions

  • Avoid excessive alcohol consumption, as it may increase the risk of side effects like dizziness or stomach upset.
  • Drink plenty of water throughout the day to prevent kidney-related side effects.

Sulfamethoxazole-Trimethoprim 800mg-160mg Contraindications

This medication is not suitable for:

  • Individuals allergic to sulfa drugs, trimethoprim, or any of the components.
  • Patients with severe liver or kidney impairment.
  • Pregnant or breastfeeding women unless specifically recommended by a healthcare provider.
  • Individuals with a history of blood disorders or folate deficiency.

Precautions and Warnings

  • Inform your doctor if you have a history of kidney, liver, or blood disorders.
  • Avoid prolonged sun exposure, as this medication may increase your sensitivity to sunlight. Use sunscreen and protective clothing.
  • Monitor for symptoms of allergic reactions, such as rash or swelling, and seek immediate medical attention if they occur.
  • Regular blood tests may be required during prolonged treatment to monitor for potential side effects.

Storage

  • Store Sulfamethoxazole-Trimethoprim 800mg-160mg tablets at room temperature, away from moisture, heat, and direct light.
  • Keep the medication in its original packaging and out of reach of children and pets.
  • Dispose of unused or expired tablets responsibly, following local disposal guidelines.

Safety Information

  • Use Sulfamethoxazole-Trimethoprim 800mg-160mg only as directed by your healthcare provider.
  • Do not skip doses or stop the medication early, as this may result in incomplete treatment and bacterial resistance.
  • Report any unusual symptoms, such as persistent stomach pain, jaundice, or difficulty breathing, to your healthcare provider immediately.
Quantity 120, 180, 240, 60
Manufacturer Piramal Healthcare
Indian Brand Bactirim DS
US Brand Name Bactrim, Septrin, Sulfamethoxazole-Trimethoprim
Generic Name Sulfamethoxazole-Trimethoprim 800mg-160mg
Dosage 800mg-160mg
Drug Type Tablets
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