Clarithromycin 500mg
Clarithromycin 500mg is a macrolide antibiotic widely prescribed to treat bacterial infections. It works by inhibiting the growth of bacteria, making it an effective solution for infections affecting the respiratory tract, skin, soft tissues, and gastrointestinal system. Clarithromycin 500mg is particularly beneficial for severe or persistent infections requiring a higher dosage. This product description covers its uses, drug interactions, food interactions, contraindications, precautions, and proper storage to ensure safe and effective use.
$2.64 – $3.23
Clarithromycin 500mg is a macrolide antibiotic widely prescribed to treat bacterial infections. It works by inhibiting the growth of bacteria, making it an effective solution for infections affecting the respiratory tract, skin, soft tissues, and gastrointestinal system. Clarithromycin 500mg is particularly beneficial for severe or persistent infections requiring a higher dosage. This product description covers its uses, drug interactions, food interactions, contraindications, precautions, and proper storage to ensure safe and effective use.
Clarithromycin 500mg is a macrolide antibiotic widely prescribed to treat bacterial infections. It works by inhibiting the growth of bacteria, making it an effective solution for infections affecting the respiratory tract, skin, soft tissues, and gastrointestinal system. Clarithromycin 500mg is particularly beneficial for severe or persistent infections requiring a higher dosage. This product description covers its uses, drug interactions, food interactions, contraindications, precautions, and proper storage to ensure safe and effective use.
Clarithromycin 500mg Uses
Clarithromycin 500mg is a versatile and potent antibiotic used for treating various bacterial infections. Below are its main uses:
- Respiratory Tract Infections:
- Pneumonia: Clarithromycin 500mg effectively treats mild to moderate cases of community-acquired pneumonia by eliminating bacteria in the lungs.
- Bronchitis: It is prescribed for bacterial infections causing acute or chronic bronchitis, reducing inflammation and improving breathing.
- Sinusitis: Clarithromycin helps treat sinus infections caused by bacteria, alleviating symptoms like congestion, facial pain, and sinus pressure.
- Tonsillitis and Pharyngitis: It is used to treat throat infections, including Streptococcus pyogenes-induced strep throat.
- Skin and Soft Tissue Infections:
- Clarithromycin 500mg helps resolve bacterial skin infections such as cellulitis, impetigo, and folliculitis, reducing swelling, redness, and discomfort.
- Ear Infections:
- It treats bacterial otitis media (middle ear infections), especially in cases where other antibiotics are ineffective or not suitable.
- Helicobacter Pylori Eradication:
- Clarithromycin 500mg, when combined with other medications like amoxicillin and proton pump inhibitors (PPIs), effectively eradicates Helicobacter pylori, a bacteria responsible for peptic ulcers and gastritis.
- Mycobacterial Infections:
- It is used for treating and preventing infections caused by non-tuberculous mycobacteria, particularly in immunocompromised patients, such as those with HIV/AIDS.
- Dental Infections:
- Clarithromycin 500mg is sometimes prescribed for dental infections, particularly when bacteria are causing gum abscesses or swelling.
- Severe or Persistent Infections:
- For bacterial infections that do not respond to lower doses, Clarithromycin 500mg offers a stronger, more effective solution.
By targeting a broad range of bacteria, Clarithromycin 500mg is an essential treatment for numerous bacterial infections, ensuring rapid relief and recovery.
Drug Interactions
Clarithromycin 500mg interacts with several medications, which can affect its effectiveness or increase the risk of adverse effects. Below are key drug interactions:
- Statins (e.g., Simvastatin, Atorvastatin):
- Clarithromycin can increase the levels of statins in the blood, leading to muscle toxicity (myopathy). Dose adjustments or temporary discontinuation of statins may be required.
- Warfarin and Anticoagulants:
- Combining Clarithromycin with warfarin or other blood thinners may increase the risk of bleeding. Regular monitoring of clotting parameters (INR) is essential.
- Calcium Channel Blockers (e.g., Amlodipine, Verapamil):
- Clarithromycin can enhance the effects of calcium channel blockers, potentially causing low blood pressure or heart complications.
- Anticonvulsants (e.g., Carbamazepine, Phenytoin):
- Clarithromycin may increase blood levels of anticonvulsants, leading to toxicity.
- Benzodiazepines (e.g., Midazolam, Triazolam):
- Combining these medications can cause excessive sedation or drowsiness due to slowed metabolism.
- Antiarrhythmic Medications (e.g., Amiodarone, Quinidine):
- Concurrent use may increase the risk of QT prolongation and heart rhythm abnormalities.
- HIV Medications (e.g., Ritonavir, Efavirenz):
- Clarithromycin levels may be altered when combined with HIV antiretroviral drugs, requiring dosage adjustments.
- Ergot Alkaloids (e.g., Ergotamine):
- Combining Clarithromycin with ergot alkaloids may lead to severe toxicity, such as ergotism (vasoconstriction and tissue damage).
- Recommendation: Inform your doctor about all medications, including supplements, before starting Clarithromycin 500mg to avoid harmful interactions.
Food Interactions
Understanding how food interacts with Clarithromycin 500mg helps maximize its effectiveness and reduce side effects:
- With or Without Food:
- Clarithromycin 500mg can be taken with or without food. However, taking it with a light meal may help prevent gastrointestinal discomfort such as nausea or vomiting.
- Grapefruit Juice:
- Avoid grapefruit juice, as it can interfere with drug metabolism, increasing Clarithromycin levels in the blood and raising the risk of side effects.
- Alcohol:
- While alcohol does not directly interact with Clarithromycin, it can worsen side effects such as dizziness, stomach upset, or fatigue. Avoid alcohol during treatment.
- Dairy Products:
- Dairy does not interfere with Clarithromycin absorption, but maintaining a balanced diet can help optimize recovery.
Recommendation: Take Clarithromycin 500mg with a glass of water and a light meal to minimize stomach upset. Avoid grapefruit juice and alcohol for the duration of treatment.
Contraindications
Certain conditions and factors may prevent the use of Clarithromycin 500mg. Below are the main contraindications:
- Hypersensitivity:
- Patients with known allergies to Clarithromycin, other macrolide antibiotics (e.g., erythromycin), or any of its components should not use this medication.
- Severe Liver Disease:
- Patients with severe hepatic impairment should avoid Clarithromycin due to the risk of worsening liver function.
- QT Prolongation and Arrhythmias:
- Patients with a history of prolonged QT intervals or ventricular arrhythmias should avoid Clarithromycin, as it may exacerbate heart rhythm issues.
- Concomitant Use of Specific Medications:
- Avoid combining Clarithromycin with ergotamine, cisapride, or colchicine due to severe toxicity risks.
- Myasthenia Gravis:
- Clarithromycin may worsen symptoms of this neuromuscular disorder.
Precautions and Warnings
To ensure safe and effective use of Clarithromycin 500mg, consider the following precautions:
- Liver and Kidney Impairment:
- Patients with mild to moderate liver or kidney issues require dosage adjustments and close monitoring.
- Heart Health:
- Clarithromycin may cause QT prolongation, leading to irregular heart rhythms. Patients with existing heart conditions need monitoring.
- Antibiotic Resistance:
- Complete the full course of treatment to prevent antibiotic resistance, even if symptoms improve early.
- Gastrointestinal Symptoms:
- Common side effects include nausea, vomiting, diarrhea, and abdominal pain. Taking the medication with food can help minimize these effects.
- Allergic Reactions:
- Discontinue use and seek immediate medical attention if you experience rash, swelling, or breathing difficulties.
- Pregnancy and Breastfeeding:
- Clarithromycin 500mg should only be used during pregnancy or breastfeeding if prescribed by a healthcare professional.
Storage
Proper storage of Clarithromycin 500mg ensures its potency and safety. Follow these guidelines:
Store at Room Temperature:
- Keep the medication at 15°C to 30°C (59°F to 86°F) in a dry environment.
- Avoid Heat and Moisture: ,Do not store Clarithromycin in humid areas, such as bathrooms or near sinks.
- Keep Away from Light:
- Store the medication in its original packaging to protect it from light exposure.
- Keep Out of Reach of Children:
- Ensure the medication is stored securely to prevent accidental ingestion.
- Check Expiry Date:
- Do not use the medication past its expiration date, as it may lose effectiveness.
Quantity | 120, 160, 40, 80 |
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Manufacturer | Abbott |
Indian Brand | Claribid 500mg |
US Brand Name | Biaxin, Clarac, Clarihexal, Clarithro, Clarithromycin, Kalixocin, Klaricid |
Generic Name | Clarithromycin |
Dosage | 500mg |
Drug Type | Tablets |
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