Saxagliptin 2.5mg Uses

Saxagliptin 2.5mg is prescribed for:

  • Type 2 Diabetes Management: Improves blood sugar control in adults with type 2 diabetes.
  • Combination Therapy: Often used alongside other diabetes medications, such as metformin or sulfonylureas, for enhanced efficacy.
  • Reduction of Postprandial Glucose Levels: Helps manage blood sugar levels after meals.

This medication is not intended for use in patients with type 1 diabetes or diabetic ketoacidosis.

How Does Saxagliptin 2.5mg Work?

Saxagliptin works by:

  • Inhibiting DPP-4 Enzymes: Prevents the breakdown of incretin hormones, which help regulate insulin production and glucose levels.
  • Increasing Insulin Secretion: Enhances insulin release in response to high blood sugar.
  • Reducing Glucose Production: Lowers the amount of glucose produced by the liver, leading to better overall glycemic control.

This mechanism helps maintain steady blood sugar levels, particularly after meals.

How to Use Saxagliptin 2.5mg

  1. Dosage: Take Saxagliptin 2.5mg exactly as prescribed by your doctor, usually once daily.
  2. Administration: Swallow the tablet whole with water, with or without food.
  3. Timing: Take the medication at the same time each day for consistent blood sugar control.
  4. Adherence: Do not skip doses or stop taking the medication without consulting your doctor.

Side Effects

Common side effects of Saxagliptin 2.5mg include:

  • Upper respiratory infections (e.g., sore throat, runny nose)
  • Headache
  • Stomach discomfort or nausea
  • Peripheral swelling

Rare but serious side effects may include severe joint pain, allergic reactions, or pancreatitis. Contact your doctor immediately if you experience symptoms such as severe abdominal pain or signs of an allergic reaction (e.g., rash, difficulty breathing).

Drug Interactions

Saxagliptin 2.5mg may interact with other medications. Inform your doctor if you are taking:

  • Insulin or other antidiabetic medications (may increase the risk of hypoglycemia)
  • Rifampin or other CYP3A4 inducers (may reduce the effectiveness of Saxagliptin)
  • Strong inhibitors of CYP3A4 (e.g., ketoconazole)
  • Medications for heart conditions or high blood pressure

Food Interactions

  • Meals: Saxagliptin can be taken with or without food, but maintaining a balanced diet supports optimal blood sugar control.
  • Alcohol: Limit alcohol consumption, as it may increase the risk of low blood sugar or other complications.

Contraindications

Saxagliptin 2.5mg is contraindicated in individuals who:

  • Are allergic to Saxagliptin or any of its components.
  • Have a history of severe allergic reactions to DPP-4 inhibitors.
  • Have type 1 diabetes or diabetic ketoacidosis.

Precautions and Warnings

  • Kidney Function: Use with caution in patients with impaired kidney function, and dosage adjustments may be required.
  • Heart Failure: Patients with a history of heart failure should consult their doctor before starting Saxagliptin.
  • Pancreatitis Risk: Report any unusual abdominal pain or symptoms of pancreatitis to your doctor immediately.
  • Pregnancy and Breastfeeding: Consult your doctor before using Saxagliptin if you are pregnant or breastfeeding.

Safety Information

  • Monitoring: Regular blood sugar monitoring and periodic HbA1c testing are recommended to assess glycemic control.
  • Medication Compliance: Consistent use as prescribed is essential for maintaining steady blood sugar levels.
  • Lifestyle Adjustments: Combine Saxagliptin with a healthy diet, regular exercise, and weight management for optimal results.

Storage

  • Store Saxagliptin 2.5mg at room temperature, away from heat, moisture, and direct sunlight.
  • Keep out of reach of children and pets.
  • Dispose of unused or expired medication responsibly.
Quantity 112, 28, 56, 84
Manufacturer AstraZeneca
Indian Brand Onglyza 2.5mg
US Brand Name Onglyza, Saxagliptin
Generic Name Saxagliptin
Dosage 2.5mg
Drug Type Tablets
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