Saxagliptin 5mg Uses

Saxagliptin 5mg is prescribed for:

  • Type 2 Diabetes Management: Helps regulate blood sugar levels in adults with type 2 diabetes.
  • Combination Therapy: Often used with other antidiabetic medications, such as metformin, for enhanced results.
  • Reduction of Postprandial Glucose Levels: Lowers blood sugar spikes after meals.

This medication is not intended for use in type 1 diabetes or diabetic ketoacidosis.

How Does Saxagliptin 5mg Work?

Saxagliptin works by:

  • Inhibiting DPP-4 Enzymes: Prevents the breakdown of incretin hormones, which regulate blood sugar levels.
  • Increasing Insulin Secretion: Enhances insulin production in response to high blood sugar levels.
  • Reducing Glucose Production: Lowers glucose production by the liver, resulting in better blood sugar control.

This dual mechanism helps maintain steady blood sugar levels throughout the day.

How to Use Saxagliptin 5mg

  1. Dosage: Take Saxagliptin 5mg as prescribed by your doctor, usually once daily.
  2. Administration: Swallow the tablet whole with water, with or without food.
  3. Timing: Take at the same time each day for consistent blood sugar regulation.
  4. Adherence: Do not skip doses or discontinue use without consulting your doctor.

Side Effects

Common side effects of Saxagliptin 5mg include:

  • Upper respiratory infections (e.g., sore throat, runny nose)
  • Headache
  • Nausea or stomach discomfort
  • Peripheral swelling

Rare but serious side effects may include joint pain, allergic reactions, or pancreatitis. Contact your doctor immediately if you experience severe abdominal pain, difficulty breathing, or swelling of the face or throat.

Drug Interactions

Saxagliptin 5mg may interact with other medications. Inform your doctor if you are taking:

  • Insulin or sulfonylureas (may increase the risk of hypoglycemia)
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)
  • Rifampin or other CYP3A4 inducers (may reduce Saxagliptin’s effectiveness)
  • Medications for heart conditions or high blood pressure

Food Interactions

  • Meals: Saxagliptin can be taken with or without food; a balanced diet supports optimal blood sugar control.
  • Alcohol: Limit alcohol consumption, as it may increase the risk of low blood sugar or other complications.

Contraindications

Saxagliptin 5mg is contraindicated in individuals who:

  • Are allergic to Saxagliptin or any of its components.
  • Have a history of severe allergic reactions to DPP-4 inhibitors.
  • Have type 1 diabetes or diabetic ketoacidosis.

Precautions and Warnings

  • Kidney Function: Patients with impaired kidney function may require dosage adjustments.
  • Heart Failure: Use with caution in individuals with a history of heart failure.
  • Pancreatitis: Report symptoms of pancreatitis, such as severe abdominal pain, to your doctor immediately.
  • Pregnancy and Breastfeeding: Consult your doctor before using Saxagliptin if you are pregnant or breastfeeding.

Safety Information

  • Monitoring: Regular blood sugar monitoring and HbA1c testing are essential to assess treatment effectiveness.
  • Medication Compliance: Consistent use is crucial for maintaining steady blood sugar levels.
  • Lifestyle Adjustments: Combine Saxagliptin with a healthy diet, regular exercise, and weight management for optimal results.

Storage

  • Store Saxagliptin 5mg at room temperature, away from heat, moisture, and direct sunlight.
  • Keep out of reach of children and pets.
  • Dispose of unused or expired medication responsibly.
Quantity 112, 28, 56, 84
Manufacturer AstraZeneca
Indian Brand Onglyza 5mg
US Brand Name Onglyza, Saxagliptin
Generic Name Saxagliptin
Dosage 5mg.
Drug Type Tablets
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