Olmesartan-Amlodipine-Hydrochlorothiazide 20mg-5mg-12.5mg Uses

This combination medication is used to:

  • Treat hypertension (high blood pressure) in patients requiring multi-drug therapy.
  • Lower the risk of cardiovascular events, such as strokes, heart attacks, or kidney damage.
  • Provide sustained blood pressure control by addressing multiple underlying mechanisms.

How Does Olmesartan-Amlodipine-Hydrochlorothiazide 20mg-5mg-12.5mg Work?

  • Olmesartan (20mg): An angiotensin II receptor blocker (ARB) that relaxes blood vessels by blocking the action of angiotensin II, a hormone that causes blood vessel constriction, thereby lowering blood pressure.
  • Amlodipine (5mg): A calcium channel blocker (CCB) that relaxes and widens blood vessels, improving blood flow and reducing the heart’s workload.
  • Hydrochlorothiazide (12.5mg): A diuretic (water pill) that helps the body eliminate excess salt and water, further reducing blood pressure and decreasing fluid retention.

Together, these three active ingredients offer a powerful and effective approach to managing hypertension.

How to Use Olmesartan-Amlodipine-Hydrochlorothiazide 20mg-5mg-12.5mg

  • Take one tablet orally, once daily, with or without food.
  • Swallow the tablet whole with water; do not crush, chew, or break it.
  • Take the medication at the same time each day for consistent results.
  • Follow your healthcare provider’s dosage instructions carefully.

Side Effects

Common side effects may include:

  • Dizziness or lightheadedness, especially when standing up quickly.
  • Fatigue or drowsiness.
  • Headache.
  • Increased urination during the initial weeks of treatment.

Rare but serious side effects include severe allergic reactions, swelling of the hands or feet, or electrolyte imbalances. Contact your healthcare provider immediately if you experience severe or persistent symptoms.

Drug Interactions

Avoid combining Olmesartan-Amlodipine-Hydrochlorothiazide with:

  • Potassium supplements or potassium-sparing diuretics, which may raise potassium levels.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs), as they may reduce the effectiveness of this medication.
  • Other blood pressure medications or diuretics, unless prescribed together by your doctor.
  • Lithium, as this combination may increase the risk of lithium toxicity.

Always inform your doctor about all medications, supplements, or herbal products you are taking to avoid potential interactions.

Food Interactions

This medication can be taken with or without food. Avoid excessive alcohol consumption, as it may enhance side effects like dizziness or lightheadedness. Limit intake of salt substitutes containing potassium.

Contraindications

Do not use this medication if you:

  • Are allergic to Olmesartan, Amlodipine, Hydrochlorothiazide, or any of the components.
  • Have severe kidney or liver impairment.
  • Are pregnant or planning to become pregnant, as this medication may harm the fetus.
  • Have anuria (inability to urinate).

Consult your doctor to ensure this medication is appropriate for your condition.

Precautions and Warnings

Before using this medication, inform your doctor if you:

  • Have a history of electrolyte imbalances, such as low potassium or sodium levels.
  • Suffer from kidney or liver disease.
  • Experience severe fluid loss (dehydration).
  • Are breastfeeding or planning to breastfeed.

Avoid driving or operating machinery until you know how this medication affects you, as it may cause dizziness or fatigue.

Safety Information

Olmesartan-Amlodipine-Hydrochlorothiazide 20mg-5mg-12.5mg is a prescription medication and should only be used under medical supervision. Do not abruptly stop taking this medication without consulting your doctor. If you miss a dose, take it as soon as you remember unless it is close to your next dose. Do not double up on doses.

Storage

Store the tablets in a cool, dry place, away from direct sunlight and moisture. Keep them out of reach of children and pets. Dispose of expired or unused medication responsibly, following local regulations.

Quantity 120, 30, 60, 90
Manufacturer Sun Pharma
Indian Brand Triolmezest
US Brand Name Olmesartan-Amlodipine-Hydrochlorothiazide, Tribenzor
Generic Name Olmesartan-Amlodipine-Hydrochlorothiazide
Dosage 20mg-5mg-12.5mg
Drug Type Tablets
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