Metformin PR 750mg

Uses of Metformin PR 750mg

Metformin PR 750mg is used to manage blood sugar levels in individuals with type 2 diabetes, either alone or in combination with other antidiabetic medications. It helps reduce the risk of complications associated with high blood sugar, such as kidney damage, nerve problems, and heart disease. It is also sometimes used in managing polycystic ovary syndrome (PCOS) to improve insulin resistance and ovulation.

How Does Metformin PR 750mg Work?

Metformin PR 750mg works by reducing glucose production in the liver, decreasing the absorption of glucose from the intestines, and improving the sensitivity of muscles and fat cells to insulin. These combined actions help lower blood sugar levels and improve glycemic control without causing significant hypoglycemia when used alone.

How to Use Metformin PR 750mg

Take Metformin PR 750mg as directed by your healthcare provider, usually once daily with an evening meal. Swallow the tablet whole with water; do not crush, chew, or break it, as this may interfere with its prolonged-release properties. If you miss a dose, take it as soon as you remember unless it is close to your next scheduled dose. Do not double the dose to make up for a missed one. Regular blood sugar monitoring and adherence to your prescribed dosage are essential for effective management.

Side Effects

Common side effects of Metformin PR 750mg include nausea, diarrhea, abdominal discomfort, and metallic taste. These symptoms are usually mild and improve as your body adjusts to the medication. Rare but serious side effects include lactic acidosis, characterized by symptoms such as extreme tiredness, muscle pain, trouble breathing, and slow or irregular heartbeat. Seek immediate medical attention if you experience severe or persistent side effects.

Drug Interactions

Metformin PR 750mg may interact with other medications, including diuretics and corticosteroids, which may increase blood sugar levels, insulin or other antidiabetic medications, which may enhance the risk of hypoglycemia, iodinated contrast agents used in imaging tests, which may increase the risk of lactic acidosis, and alcohol, which may also increase the risk of lactic acidosis. Always inform your healthcare provider about all medications, supplements, and herbal products you are using.

Food Interactions

Take Metformin PR 750mg with meals to reduce the risk of gastrointestinal side effects. Avoid excessive alcohol consumption, as it can increase the risk of lactic acidosis and affect blood sugar control. Maintain a balanced diet and exercise routine as advised by your healthcare provider.

Contraindications

Metformin PR 750mg is contraindicated in individuals with severe kidney disease or significantly impaired renal function, conditions associated with increased risk of lactic acidosis, such as severe liver disease or heart failure, known hypersensitivity to Metformin or any other ingredients in the formulation, and individuals undergoing imaging tests with iodinated contrast agents without appropriate precautions. Your healthcare provider will evaluate your medical history to ensure this medication is safe for you.

Precautions and Warnings

Regular monitoring of kidney function is recommended, as Metformin is excreted by the kidneys and may accumulate in cases of impaired renal function. Use with caution in individuals with conditions predisposing them to dehydration or reduced kidney function, such as severe infections or surgery. Consult your healthcare provider if you plan to become pregnant or are breastfeeding, as alternative treatments may be recommended. Inform your doctor if you experience unexplained symptoms such as rapid breathing, unusual drowsiness, or muscle pain, which may indicate lactic acidosis.

Safety Information

Seek immediate medical attention if you experience symptoms of lactic acidosis, such as severe weakness, trouble breathing, or irregular heartbeat. Overdose symptoms may include severe hypoglycemia or lactic acidosis. Contact a healthcare provider or poison control center immediately if overdose occurs.

Storage

Store Metformin PR 750mg tablets at room temperature, between 20–25°C (68–77°F). Keep the medication in a dry place, away from direct sunlight and excessive moisture. Avoid storing it in bathrooms. Ensure the medication is out of reach of children and pets. Dispose of unused or expired tablets responsibly, following local waste disposal guidelines.