Levetiracetam 100mg Oral Solution 100ml
In StockLevetiracetam Oral Solution is a prescription anticonvulsant used to help control selected seizure disorders. Confirm the concentration on the product label and measure every dose with an appropriate oral dosing device.
| Active Ingredient: | Levetiracetam |
|---|---|
| Indication: | Epilepsy |
| Strength: | 100mg-100ml |
| Dosage Form: | Oral Liquid Solution |
| Manufacturer: | Sun Pharma |
Levetiracetam 100mg Oral Solution – Quick Overview
Levetiracetam oral solution 100mg/mL is a prescription antiepileptic (anti-seizure) medication used to treat partial-onset, myoclonic, and primary generalized tonic-clonic seizures. It works by stabilizing electrical activity in the brain. This liquid formulation is prescription-only and should be dosed exactly as directed by a licensed healthcare provider, especially in children.
Medical Supervision & Regulatory Status
Levetiracetam oral solution is a prescription-only medication in the United States, regulated by the FDA. It is not available over the counter. Medical supervision is essential because dosing is calculated by body weight in pediatric patients and must be adjusted for kidney function in all patients.
Clinical Context
Levetiracetam oral solution treats several seizure types, including partial-onset seizures in patients as young as 1 month, myoclonic seizures in juvenile myoclonic epilepsy, and primary generalized tonic-clonic seizures in idiopathic generalized epilepsy.
Uncontrolled seizures can pose serious safety risks and disrupt daily functioning, making consistent, correctly dosed antiepileptic therapy clinically important, particularly in young children who require the liquid formulation.
The oral solution form is specifically used for patients who cannot swallow tablets, including infants, young children, and patients weighing 20kg or less, who the FDA label specifies must use this liquid formulation.
How Levetiracetam Works
Levetiracetam belongs to a chemically distinct antiepileptic drug class, unrelated to other seizure medications. Its exact mechanism is not fully understood, but it is believed to bind to a synaptic vesicle protein (SV2A) involved in regulating neurotransmitter release.
By modulating this protein, levetiracetam is thought to help normalize abnormal electrical signaling in the brain that leads to seizures.
This distinct mechanism allows levetiracetam to be used as monotherapy or add-on therapy, giving doctors an additional option when treating various seizure types.
What is Levetiracetam 100mg Oral Solution?
- Drug Class: Antiepileptic drug (AED), pyrrolidine derivative
- Active Ingredient: Levetiracetam, 100mg per mL
- Mechanism: Believed to bind SV2A, modulating neurotransmitter release
- Form: Oral solution, clear, colorless, grape-flavored, 100mg/mL concentration, 100ml bottle
- Dosing Frequency: Twice daily, with dose calculated by weight in pediatric patients
- Regulatory Status: FDA-approved, prescription required (Rx only)
Uses / Indications
- Partial-onset seizures: Treats this seizure type in patients 1 month of age and older
- Myoclonic seizures: Add-on therapy for juvenile myoclonic epilepsy in patients 12 years and older
- Primary generalized tonic-clonic seizures: Add-on therapy in idiopathic generalized epilepsy, patients 6 years and older
How to Use / Dosage
Levetiracetam oral solution is measured precisely using an appropriate dosing device and given twice daily, with or without food. In pediatric patients, the dose is calculated using the formula: (daily dose in mg/kg/day × patient weight in kg) ÷ 100mg/mL = total daily volume. Only your doctor can determine the correct dose based on age, weight, seizure type, and kidney function.
If a dose is missed, take it as soon as remembered unless close to the next dose — do not double up. Do not stop taking levetiracetam suddenly, as abrupt withdrawal can increase the risk of seizures returning or worsening, including status epilepticus.
Side Effects
Most patients tolerate levetiracetam reasonably well, though side effects should be discussed with a healthcare provider.
Common side effects may include drowsiness, weakness, dizziness, and irritability, particularly in children.
Serious side effects can include significant behavioral or mood changes (including aggression or agitation), severe allergic reactions, and rare but serious skin reactions.
Emergency Warning Signs — seek medical care immediately if you experience:
- New or worsening thoughts of self-harm or suicide
- Severe mood or behavior changes, including aggression
- Swelling of the face, lips, tongue, or throat
- Severe skin rash, blistering, or peeling
- Signs of severe allergic reaction (difficulty breathing, hives)
- Unusual weakness or difficulty walking
Warnings & Precautions
Levetiracetam oral solution is contraindicated in patients with known hypersensitivity to levetiracetam, given reported cases of anaphylaxis and angioedema; it carries a warning for behavioral changes, including irritability, aggression, and psychotic symptoms, which require close monitoring, especially in children.
There are limited significant drug-drug interactions with levetiracetam, though caution is advised when combining with other CNS-depressant medications, as sedative effects may be additive; kidney function should be assessed before starting therapy since dosing depends on creatinine clearance.
Levetiracetam plasma levels may decrease during pregnancy, requiring closer monitoring, and animal data suggest possible fetal risk at high doses; discuss breastfeeding plans with your doctor. Dosing must be individualized in patients with renal impairment based on calculated creatinine clearance.
Who Should Not Use This Medication
- Individuals with known hypersensitivity to levetiracetam
- Patients with a history of anaphylaxis or angioedema from levetiracetam
- Patients requiring dose adjustment for significant renal impairment who have not been properly assessed
- Use without medical supervision in children under 1 month of age
Storage Instructions
Store at room temperature, 59°F to 86°F (15°C to 30°C), away from heat and light. Dispense in a tight, light-resistant container with a child-resistant closure. Keep out of reach of children and pets.
Frequently Asked Questions
What is the cost of Levetiracetam 100mg Oral Solution without insurance?
Generic levetiracetam oral solution is generally more affordable than brand-name Keppra. The cost without insurance depends on the seller, brand availability, and pack size, and may also vary by location and available discounts.
How can I order Levetiracetam Oral Solution online?
A valid prescription specifying this liquid formulation and strength is required. Typically, you upload your prescription or have your doctor send it to a licensed pharmacy for delivery. Always use verified, licensed pharmacies for safety.
Is Levetiracetam Oral Solution available over the counter?
No, it is not available over the counter in the United States or most countries. It requires a prescription due to the need for individualized, weight-based, or renal-adjusted dosing.
Does Levetiracetam Oral Solution require a prescription?
Yes, a prescription is required. Medical evaluation ensures the correct dose is calculated based on weight (in children), seizure type, and kidney function.
How long does it take for Levetiracetam Oral Solution to work?
Levetiracetam can begin reducing seizure activity relatively quickly once an effective dose is reached, though your doctor may gradually titrate the dose over several weeks to find the right level for you or your child.
Can I stop giving Levetiracetam Oral Solution once seizures improve?
No — stopping suddenly can increase the risk of seizures returning or worsening, including status epilepticus. Any dose changes must be guided by your doctor.
Does Levetiracetam Oral Solution interact with other medications?
Levetiracetam has relatively few major drug interactions, but combining it with other sedating medications may increase drowsiness. Always share your full medication list with your doctor or pharmacist.
References
- DailyMed – Levetiracetam Oral Solution 100mg/mL Label (NIH/NLM)
- MedlinePlus – Levetiracetam
- FDA – Levetiracetam Oral Solution Medication Guide
Resources
Medical Disclaimer:
This content is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. Consult a qualified specialist or physician before using Levetiracetam Oral Solution.
Prescription Required (Rx) to Buy?
This medication is not available over the counter. A valid prescription from a licensed healthcare
professional is required. Always consult your doctor before use.
| Quantity | 1, 2, 3, 4 |
|---|---|
| Indication | Epilepsy |
| Active Ingredient | Levetiracetam |
| Pharmaceutical Form | Oral Liquid Solution |
| Manufacturer | Sun Pharma |
| Indian Brand | Levipil Syrup 100ml |
| US Brand Name | Levetiracetam |
| Generic Name | Levetiracetam |
| Dosage | 100mg-100ml |
| Drug Type | Bottles |
