Uses of Glyburide (Glibenclamide) 1.25mg

Glyburide 1.25mg is used to:

  • Manage Type 2 Diabetes Mellitus: Helps lower blood sugar levels in adults with type 2 diabetes.
  • Prevent Diabetes-Related Complications: Reduces the risk of long-term complications, such as nerve damage, kidney problems, and cardiovascular disease.

This medication is not suitable for treating type 1 diabetes or diabetic ketoacidosis.

How Does Glyburide (Glibenclamide) 1.25mg Work?

Glyburide works by:

  • Stimulating the pancreas to produce more insulin, thereby lowering blood sugar levels.
  • Enhancing the body’s response to insulin, improving the utilization of glucose by the cells.

This dual action makes Glyburide effective in managing blood sugar levels in individuals with type 2 diabetes.

How to Use Glyburide (Glibenclamide) 1.25mg

  • Dosage: The typical starting dose is 1.25mg once daily, usually taken with breakfast or the first main meal of the day. Your doctor may adjust the dose based on your response and blood sugar levels.
  • Administration: Swallow the tablet whole with water. Avoid crushing or chewing the tablet.
  • Timing: Take the medication at the same time each day to maintain consistent blood sugar control.
  • Missed Dose: If you miss a dose, take it as soon as you remember, unless it is close to the next dose. Avoid doubling the dose to make up for the missed one.

Always follow your healthcare provider’s instructions for safe and effective use.

Side Effects

Common side effects of Glyburide include:

  • Nausea or upset stomach
  • Dizziness or headache
  • Weight gain
  • Increased sensitivity to sunlight

Rare but serious side effects include:

  • Hypoglycemia (low blood sugar), with symptoms such as sweating, shakiness, confusion, or fainting
  • Allergic reactions (rash, itching, or swelling)
  • Liver dysfunction, with signs such as yellowing of the skin or eyes (jaundice)

Seek medical attention if you experience severe or persistent side effects.

Drug Interactions

Glyburide may interact with other medications, affecting its efficacy or increasing the risk of side effects. Common interactions include:

  • Insulin or Other Antidiabetic Medications: May increase the risk of hypoglycemia.
  • Beta-Blockers (e.g., Metoprolol): Can mask the symptoms of low blood sugar.
  • NSAIDs (e.g., Ibuprofen): May enhance the blood sugar-lowering effect.
  • Diuretics (e.g., Furosemide): Can reduce the effectiveness of Glyburide.
  • Corticosteroids: May increase blood sugar levels, reducing Glyburide’s effectiveness.

Inform your doctor about all medications, supplements, and herbal products you are taking.

Food Interactions

Glyburide can be taken with or without food, but consider the following:

  • Alcohol: Can increase the risk of low blood sugar and should be consumed in moderation.
  • High-Sugar Foods: May counteract the blood sugar-lowering effects of the medication.

Discuss dietary considerations with your healthcare provider to optimize your treatment plan.

Contraindications

Glyburide is contraindicated in the following cases:

  • Known hypersensitivity to Glyburide or other sulfonylureas.
  • Type 1 diabetes or diabetic ketoacidosis.
  • Severe liver or kidney dysfunction.
  • Pregnancy or breastfeeding, unless specifically prescribed by a doctor.

Your healthcare provider will assess your medical history to determine if Glyburide is suitable for you.

Precautions and Warnings

  • Hypoglycemia Risk: Be cautious of low blood sugar, especially if skipping meals, overexerting, or consuming alcohol. Carry a source of fast-acting sugar, such as glucose tablets, in case of symptoms.
  • Regular Monitoring: Blood sugar levels should be monitored regularly to assess treatment effectiveness.
  • Sun Sensitivity: Protect your skin from excessive sun exposure, as Glyburide may increase sensitivity.
  • Driving and Operating Machinery: Avoid activities requiring alertness if you experience dizziness or hypoglycemia.
  • Pregnancy and Breastfeeding: Discuss potential risks with your doctor, as Glyburide may not be suitable during these periods.

Safety Information

  • Emergency Situations: Seek immediate medical attention if you experience severe hypoglycemia or an allergic reaction.
  • Overdose: Symptoms of overdose include severe low blood sugar, confusion, or loss of consciousness. Contact a healthcare provider immediately if overdose occurs.
  • Regular Monitoring: Routine follow-ups with your doctor are essential to adjust dosage and monitor overall health.
  • Storage Precautions: Keep the medication out of reach of children and pets to prevent accidental ingestion.

Storage

  • Temperature: Store Glyburide 1.25mg tablets at room temperature, between 20–25°C (68–77°F).
  • Moisture and Light: Keep the medication in a dry place, away from direct sunlight and moisture. Avoid storing it in bathrooms.
  • Safety: Ensure the medication is securely stored to prevent misuse.
  • Disposal: Dispose of unused or expired tablets responsibly, following local guidelines.

By adhering to the recommended usage, storage, and safety guidelines, Glyburide (Glibenclamide) 1.25mg effectively manages blood sugar levels and reduces the risk of complications in type 2 diabetes. Always consult your healthcare provider for personalized advice and support.

Quantity 120, 180, 240, 60
Manufacturer Aristo
Indian Brand Glybovin 1.25mg
US Brand Name Glyburide/Glibenclamide
Generic Name Glyburide/Glibenclamide
Dosage 1.25mg
Drug Type Tablets
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