Overview

Dabigatran Etexilate Mesilate 110mg acts as a direct thrombin inhibitor, which plays a crucial role in the blood coagulation process. By inhibiting this key protein, Dabigatran effectively prevents the formation of blood clots, thereby mitigating the risk of serious events such as strokes and pulmonary embolisms.

Dabigatran Etexilate Mesilate 110mg Uses

Dabigatran Etexilate Mesilate 110mg is prescribed for:

  • Prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation.
  • Treatment and prevention of deep venous thrombosis (DVT) and pulmonary embolism (PE), particularly following orthopedic surgery.
  • Prevention of clot formation in patients who are at an elevated risk due to existing cardiovascular conditions or previous incidents of clots.

How Dabigatran Etexilate Mesilate 110mg Works

Dabigatran directly inhibits thrombin (Factor IIa), a crucial enzyme in the clotting process that converts fibrinogen to fibrin, the main protein that forms the clot structure. By blocking this enzyme, Dabigatran prevents the development of blood clots, offering a potent protection against thromboembolic diseases.

How to Use Dabigatran Etexilate Mesilate 110mg

  • Dabigatran should be taken orally, with a full glass of water. It can be taken with or without food.
  • It is crucial to take this medication exactly as prescribed by your healthcare provider, typically twice a day.
  • Do not open, chew, or break the capsules; swallow them whole to ensure the medication is released properly.
  • Consistency in timing and adherence to the prescribed dosage are key to maintaining the effectiveness and safety of the treatment.

Side Effects

Common side effects of Dabigatran Etexilate Mesilate 110mg include:

  • Stomach pain or upset
  • Indigestion or heartburn
  • Nausea

Serious side effects that require immediate medical attention:

  • Signs of bleeding, such as unexpected bleeding or bleeding that lasts a long time, blood in the urine, coughing up blood, or vomit that looks like coffee grounds.
  • Signs of a serious allergic reaction, including rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Drug Interactions

Dabigatran has the potential to interact with:

  • Other anticoagulants and antiplatelet agents, increasing the risk of bleeding.
  • Certain antifungal or anti-HIV medications that may affect how dabigatran is metabolized.
  • Herbal supplements like St. John’s Wort, which can reduce the effectiveness of dabigatran.

Inform your doctor about all other medications you are taking to manage potential interactions effectively.

Precautions and Warnings

  • Kidney Function: Dabigatran is contraindicated in patients with severe renal impairment and should be used with caution in those with mild to moderate renal impairment.
  • Bleeding Risks: As with all anticoagulants, there is a significant risk of bleeding; close monitoring for signs of bleeding is essential.
  • Surgery and Dental Procedures: Inform surgeons or dentists about your dabigatran use, as it may need to be stopped temporarily depending on your bleeding risk and the type of procedure.

Storage

  • Store at room temperature away from moisture and heat.
  • Keep the bottle tightly closed when not in use to protect from moisture. Dabigatran capsules are sensitive to moisture.

Dabigatran Etexilate Mesilate 110mg offers effective and convenient anticoagulation for patients at risk of thromboembolic events, with a simplified dosing regimen that does not require INR monitoring. It is crucial to follow medical advice closely, especially regarding dosing and potential interactions, to ensure the safety and effectiveness of the treatment.

Quantity 120, 180, 240, 60
Manufacturer Boehringer
Indian Brand Pradaxa 110mg
US Brand Name Dabigatran Etexilate Mesilate | Pradaxa
Generic Name Dabigatran Etexilate Mesilate
Dosage 110mg
Drug Type Capsules
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