Carbidopa-Levodopa-Entacapone 100mg (25mg-100mg-200mg)

Carbidopa-Levodopa-Entacapone 100mg Uses

Carbidopa-Levodopa-Entacapone 100mg (25mg-100mg-200mg) is prescribed for:

• Parkinson’s Disease: Effectively manages motor symptoms, including rigidity, tremors, and slowness of movement.
• Fluctuations in Symptom Control: Reduces “off” periods when Parkinson’s symptoms worsen due to low dopamine levels.

The addition of Entacapone enhances the effectiveness of Levodopa, offering longer-lasting relief.

How Does Carbidopa-Levodopa-Entacapone 100mg Work?

This combination medication contains three active ingredients:

• Levodopa: Converts into dopamine in the brain, replenishing low levels and improving motor function.
• Carbidopa: Prevents the breakdown of Levodopa in the bloodstream, ensuring more of the medication reaches the brain while reducing side effects like nausea.
• Entacapone: Inhibits the COMT enzyme, prolonging the effects of Levodopa by reducing its breakdown in the body, resulting in more sustained symptom control.

Together, these ingredients enhance dopamine levels in the brain, reducing motor fluctuations and improving overall quality of life.

How to Use Carbidopa-Levodopa-Entacapone 100mg

1. Dosage: Take Carbidopa-Levodopa-Entacapone 100mg as prescribed by your doctor. The dosage depends on your condition, previous treatment response, and medical history.
2. Administration: Swallow the tablet whole with water; do not crush, chew, or split it.
3. Timing: Take the medication at the same times daily to maintain consistent blood levels.
4. Food: You may take it with or without food, but avoid high-protein meals near dosing as they may interfere with Levodopa’s absorption.

Side Effects

Common side effects of Carbidopa-Levodopa-Entacapone 100mg include:

• Nausea or vomiting
• Dizziness or lightheadedness
• Dry mouth
• Diarrhea
• Involuntary movements (dyskinesia)

Serious side effects, such as hallucinations, confusion, mood changes, or severe diarrhea, should be reported to your healthcare provider immediately.

Drug Interactions

Carbidopa-Levodopa-Entacapone 100mg may interact with other medications, potentially affecting its effectiveness or increasing side effects. Inform your doctor if you are taking:

• MAO inhibitors (e.g., phenelzine, tranylcypromine)
• Antipsychotic medications
• Iron supplements (may reduce absorption)
• Blood pressure medications

Food Interactions

Avoid consuming high-protein meals close to the time of taking Carbidopa-Levodopa-Entacapone 100mg, as protein can interfere with Levodopa’s absorption. Spacing protein intake evenly throughout the day can help maintain medication effectiveness.

Contraindications

Carbidopa-Levodopa-Entacapone 100mg is contraindicated in individuals who:

• Are allergic to Carbidopa, Levodopa, Entacapone, or any other components of the medication
• Have narrow-angle glaucoma
• Have severe liver impairment
• Are taking non-selective MAO inhibitors

Precautions and Warnings

• Pregnancy and Breastfeeding: Consult your doctor if you are pregnant, planning to conceive, or breastfeeding, as the medication may affect the baby.
• Driving and Machinery: Avoid activities requiring alertness, such as driving, until you understand how the medication affects you, as it may cause dizziness or drowsiness.
• Monitoring: Regular check-ups are necessary to monitor your condition, liver function, and potential side effects.
• Sudden Discontinuation: Do not stop taking the medication abruptly, as it may worsen symptoms or cause withdrawal effects.

Storage

Store Carbidopa-Levodopa-Entacapone 100mg at room temperature, away from heat, moisture, and direct sunlight. Keep the medication out of reach of children and pets. Dispose of unused or expired medication responsibly.