Carbidopa-Levodopa 50mg-200mg CR Uses

Carbidopa-Levodopa 50mg-200mg CR is prescribed to:

  • Parkinson’s Disease: Effectively manages motor symptoms, including rigidity, tremors, and bradykinesia (slowness of movement).
  • Parkinsonism: Treats Parkinson-like symptoms caused by other medical conditions or medications.

The controlled-release formulation is ideal for providing extended symptom control throughout the day.

How Does Carbidopa-Levodopa 50mg-200mg CR Work?

Carbidopa-Levodopa 50mg-200mg CR combines two active components:

  • Levodopa: Converts into dopamine in the brain, replenishing low levels to improve motor function and control symptoms of Parkinson’s disease.
  • Carbidopa: Prevents the breakdown of Levodopa in the bloodstream before it reaches the brain, enhancing its effectiveness and reducing side effects like nausea.

The controlled-release formulation allows the medication to be released gradually, providing sustained therapeutic effects and reducing the frequency of dosing.

How to Use Carbidopa-Levodopa 50mg-200mg CR

  1. Dosage: Take Carbidopa-Levodopa 50mg-200mg CR as prescribed by your healthcare provider. Dosage will depend on your condition and response to treatment.
  2. Administration: Swallow the tablet whole with water; do not crush, chew, or split it, as this will disrupt the controlled-release mechanism.
  3. Timing: Take the medication at regular intervals as directed by your doctor to maintain steady drug levels.
  4. Food: You may take it with or without food, but avoid high-protein meals near dosing, as they can interfere with the absorption of Levodopa.

Side Effects

Common side effects of Carbidopa-Levodopa 50mg-200mg CR include:

  • Nausea or vomiting
  • Dizziness or lightheadedness
  • Drowsiness or fatigue
  • Dry mouth
  • Involuntary movements (dyskinesia)

Severe side effects, such as hallucinations, confusion, mood changes, or irregular heartbeats, should be reported to your doctor immediately.

Drug Interactions

Carbidopa-Levodopa 50mg-200mg CR may interact with other medications, affecting its effectiveness or increasing side effects. Inform your doctor if you are taking:

  • MAO inhibitors (e.g., phenelzine, tranylcypromine)
  • Antipsychotic medications
  • Iron supplements (may reduce absorption)
  • Blood pressure-lowering drugs

Food Interactions

Avoid consuming high-protein meals around the time of taking Carbidopa-Levodopa 50mg-200mg CR, as protein can interfere with the absorption of Levodopa. Spacing protein intake evenly throughout the day can help optimize the medication’s effectiveness.

Contraindications

Carbidopa-Levodopa 50mg-200mg CR is contraindicated in individuals who:

  • Are allergic to Carbidopa, Levodopa, or any other ingredients in the medication
  • Have narrow-angle glaucoma
  • Are taking non-selective MAO inhibitors

Precautions and Warnings

  • Pregnancy and Breastfeeding: Consult your doctor if you are pregnant, planning to conceive, or breastfeeding, as this medication may affect the baby.
  • Sudden Discontinuation: Do not stop taking the medication abruptly, as it may worsen symptoms of Parkinson’s disease or cause withdrawal effects.
  • Driving and Machinery: Avoid driving or operating machinery until you understand how the medication affects you, as it may cause dizziness or drowsiness.
  • Monitoring: Regular check-ups and blood tests may be required to monitor your condition and adjust the dosage if necessary.

Storage

Store Carbidopa-Levodopa 50mg-200mg CR at room temperature, away from moisture, heat, and direct sunlight. Keep it out of reach of children and pets. Dispose of unused or expired medication responsibly.

Quantity 100, 200, 300, 400
Manufacturer Sun Pharma
Indian Brand Syndopa CR 250mg
US Brand Name Carbidopa-Levodopa
Generic Name Carbidopa-Levodopa
Dosage 50mg-200mg
Drug Type Tablets
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