Carbidopa-Levodopa 25mg-100mg CR Uses

Carbidopa-Levodopa 25mg-100mg CR is prescribed for:

  • Parkinson’s Disease: Manages motor symptoms like rigidity, tremors, and impaired movement.
  • Parkinsonism: Treats Parkinson-like symptoms caused by other medical conditions or medications.

The controlled-release formulation offers longer-lasting symptom relief, making it ideal for patients requiring sustained effects throughout the day.

How Does Carbidopa-Levodopa 25mg-100mg CR Work?

This medication combines two active ingredients:

  • Levodopa: Converts into dopamine in the brain to replenish low levels, improving motor function.
  • Carbidopa: Prevents Levodopa from breaking down in the bloodstream before it reaches the brain, increasing its effectiveness and reducing side effects like nausea.

The controlled-release formulation ensures a gradual release of the medication, providing consistent symptom management and minimizing fluctuations in dopamine levels.

How to Use Carbidopa-Levodopa 25mg-100mg CR

  1. Dosage: Take Carbidopa-Levodopa 25mg-100mg CR as prescribed by your doctor. The dosing schedule depends on your medical condition and response to treatment.
  2. Administration: Swallow the tablet whole with water. Do not crush, chew, or split the tablet, as this will disrupt the controlled-release mechanism.
  3. Timing: Take the medication at the same time daily to maintain consistent drug levels.
  4. Food: You may take it with or without food, but high-protein meals should be avoided close to dosing, as they can interfere with absorption.

Side Effects

Common side effects of Carbidopa-Levodopa 25mg-100mg CR include:

  • Nausea or vomiting
  • Drowsiness or dizziness
  • Dry mouth
  • Lightheadedness
  • Involuntary movements (dyskinesia)

Rare but severe side effects, such as hallucinations, mood changes, or worsening of Parkinson’s symptoms, require immediate medical attention.

Drug Interactions

Carbidopa-Levodopa 25mg-100mg CR may interact with other medications, affecting its effectiveness or increasing side effects. Inform your doctor if you are taking:

  • MAO inhibitors (e.g., phenelzine, tranylcypromine)
  • Antipsychotic medications
  • Iron supplements (may reduce absorption)
  • Blood pressure-lowering drugs

Food Interactions

Avoid consuming high-protein meals around the time of taking Carbidopa-Levodopa 25mg-100mg CR, as they may interfere with Levodopa’s absorption. Spacing protein intake throughout the day can help maintain the medication’s effectiveness.

Contraindications

Carbidopa-Levodopa 25mg-100mg CR is contraindicated in individuals who:

  • Are allergic to Carbidopa, Levodopa, or any other components of the medication
  • Have narrow-angle glaucoma
  • Are taking non-selective MAO inhibitors

Precautions and Warnings

  • Pregnancy and Breastfeeding: Consult your doctor before using this medication if you are pregnant, planning to conceive, or breastfeeding.
  • Sudden Discontinuation: Do not stop taking the medication abruptly, as this can worsen Parkinson’s symptoms or cause withdrawal effects.
  • Driving and Machinery: Avoid activities requiring alertness until you know how the medication affects you, as it may cause dizziness or drowsiness.
  • Monitoring: Regular follow-ups with your doctor are necessary to adjust the dosage and monitor for side effects.

Storage

Store Carbidopa-Levodopa 25mg-100mg CR at room temperature, away from moisture, heat, and direct sunlight. Keep it out of reach of children and pets. Dispose of expired or unused medication responsibly.

Quantity 150, 300, 450, 600
Manufacturer Sun Pharma
Indian Brand Syndopa CR 125mg
US Brand Name Carbidopa-Levodopa, Sinemet
Generic Name Carbidopa-Levodopa
Dosage 25mg-100mg
Drug Type Tablets
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