Zonisamide 100mg

Zonisamide 100mg Uses

Zonisamide 100mg is prescribed to:

• Treat partial-onset seizures in adults and children with epilepsy.
• Provide adjunctive therapy for seizures when other medications alone are insufficient.
• Stabilize brain activity to reduce seizure frequency.

How Does Zonisamide 100mg Work

Zonisamide works by blocking voltage-dependent sodium and calcium channels in the brain. This dual action helps stabilize the brain’s electrical activity and prevents abnormal nerve firing that causes seizures. Additionally, it modulates neurotransmitter release, further reducing seizure activity.

How to Use Zonisamide 100mg

• Take Zonisamide 100mg as directed by your healthcare provider, typically once or twice daily.
• Swallow the capsule whole with water, with or without food.
• Do not crush or chew the capsule, as this may alter its effectiveness.
• Continue taking the medication regularly, even if you feel well, to maintain seizure control.
• Do not abruptly stop taking Zonisamide without consulting your doctor, as this may worsen seizures.

Side Effects

Common side effects may include:

• Drowsiness or fatigue
• Dizziness or lightheadedness
• Nausea or upset stomach
• Loss of appetite or weight loss

Rare but serious side effects include:

• Kidney stones, characterized by severe pain in the back or side and blood in urine
• Severe skin reactions, such as Stevens-Johnson syndrome
• Changes in mood or behavior, including depression or suicidal thoughts
• Increased body temperature and reduced sweating, especially in children

Drug Interactions

Zonisamide 100mg may interact with:

• Other antiepileptic medications, such as phenytoin or carbamazepine, which may alter its effectiveness.
• Central nervous system depressants, such as alcohol or sedatives, which can increase drowsiness.
• Carbonic anhydrase inhibitors, which may increase the risk of kidney stones.

Food Interactions

• There are no significant food restrictions, but staying hydrated is essential to reduce the risk of kidney stones.
• Avoid alcohol consumption during treatment, as it can enhance side effects like dizziness and drowsiness.

Zonisamide 100mg Contraindications

This medication is not suitable for:

• Individuals allergic to Zonisamide, sulfonamides, or any other components of the capsule.
• Patients with severe liver or kidney impairment without medical supervision.
• Individuals with a history of severe allergic reactions to sulfa drugs.

Precautions and Warnings

• Inform your doctor if you have a history of kidney stones, liver disease, or mental health conditions.
• Use cautiously in children, as they may be more prone to overheating and reduced sweating.
• Pregnant or breastfeeding women should consult their doctor before taking Zonisamide.
• Regular monitoring of kidney function and blood levels may be required during treatment.

Storage

• Store Zonisamide 100mg capsules at room temperature, away from moisture, heat, and direct sunlight.
• Keep the capsules in their original packaging and out of reach of children and pets.
• Dispose of unused or expired capsules responsibly, following local disposal regulations.

Safety Information

• Use Zonisamide 100mg only as directed by your healthcare provider.
• Do not skip doses or stop taking the medication without medical advice.
• Report any unusual symptoms, such as severe skin reactions, mood changes, or kidney stone symptoms, to your doctor immediately.