Trientine Hydrochloride 250mg

Trientine Hydrochloride 250mg Uses

Trientine Hydrochloride 250mg is used to:

• Treat Wilson’s disease by reducing excessive copper accumulation in the body.
• Manage symptoms of copper toxicity, including liver damage, neurological complications, and other organ dysfunctions.

It is often prescribed for patients who cannot tolerate penicillamine or require an alternative therapy for copper chelation.

How Does Trientine Hydrochloride 250mg Work?

Trientine Hydrochloride is a chelating agent that binds to excess copper in the body, forming a complex that can be excreted through the urine. This process helps lower copper levels in tissues, reducing the risk of copper toxicity and preventing damage to the liver, brain, and other organs.

How to Use Trientine Hydrochloride 250mg

• Take the prescribed dose on an empty stomach, at least 1 hour before or 2 hours after meals.
• Swallow the capsule whole with water. Do not crush, chew, or open the capsule.
• Follow your doctor’s dosing instructions carefully, typically 2-4 times daily.
• Avoid taking the medication with food or supplements containing iron or calcium, as they may interfere with absorption.

Side Effects

Common side effects may include:

• Nausea
• Vomiting
• Abdominal discomfort
• Diarrhea

Rare but serious side effects include anemia, allergic reactions, or worsening neurological symptoms. Contact your healthcare provider immediately if you experience severe or persistent symptoms.

Drug Interactions

Avoid taking Trientine Hydrochloride with:

• Iron or calcium supplements, as they can reduce the medication’s effectiveness.
• Other chelating agents or medications without consulting your doctor.

Always inform your healthcare provider about all medications, supplements, or vitamins you are taking to avoid potential interactions.

Food Interactions

Do not take Trientine Hydrochloride with meals or foods high in iron or calcium, such as dairy products or fortified cereals. Ensure at least a 2-hour gap between the medication and such foods to maximize its absorption and effectiveness.

Contraindications

Do not use this medication if you:

• Are allergic to Trientine Hydrochloride or any of its components.
• Have a condition unrelated to Wilson’s disease that involves low copper levels.

Consult your doctor to determine if Trientine Hydrochloride 250mg is suitable for you.

Precautions and Warnings

Before starting Trientine Hydrochloride, inform your doctor if you:

• Have a history of anemia or other blood disorders.
• Are pregnant, planning to become pregnant, or breastfeeding.
• Are experiencing worsening neurological symptoms.

Regular monitoring of blood and urine tests is recommended to ensure the medication is working effectively and to detect any potential side effects.

Safety Information

Trientine Hydrochloride 250mg is a prescription medication and should only be used under medical supervision. Do not share this medication with others. If you miss a dose, take it as soon as you remember unless it is close to the next scheduled dose. Do not double up on doses.

Storage

Store Trientine Hydrochloride 250mg capsules in a cool, dry place, away from direct sunlight and moisture. Keep them out of reach of children and pets. Dispose of unused or expired medication responsibly, following local regulations.