Sitagliptin 50mg Uses

Sitagliptin 50mg is prescribed to:

  • Improve blood sugar control in adults with type 2 diabetes mellitus.
  • Enhance the effects of other antidiabetic medications, such as metformin or insulin.
  • Support a diabetes management plan, reducing the risk of complications like cardiovascular disease and neuropathy.

How Does Sitagliptin 50mg Work

Sitagliptin inhibits the DPP-4 enzyme, which breaks down incretin hormones in the body. These hormones stimulate insulin secretion in response to meals and reduce glucose production by the liver. By preserving incretin activity, Sitagliptin helps lower fasting and post-meal blood sugar levels effectively.

How to Use Sitagliptin 50mg

  • Take Sitagliptin 50mg exactly as prescribed by your healthcare provider, typically once daily.
  • Swallow the tablet whole with water, with or without food.
  • Adhere to a consistent dosing schedule for optimal blood sugar control.
  • Continue to follow a healthy diet and exercise plan as recommended by your healthcare provider.

Side Effects

Common side effects may include:

  • Headache or dizziness
  • Upper respiratory infections, such as a sore throat or runny nose
  • Stomach discomfort, including nausea or diarrhea

Rare but serious side effects include:

  • Pancreatitis, with symptoms like severe abdominal pain, nausea, or vomiting.
  • Severe allergic reactions, such as rash, swelling, or difficulty breathing.
  • Joint pain, which can be severe or disabling.

Drug Interactions

Sitagliptin 50mg may interact with:

  • Other antidiabetic medications, increasing the risk of hypoglycemia (low blood sugar).
  • Medications that affect kidney function, as Sitagliptin is primarily excreted by the kidneys.
  • Digoxin, a heart medication, which may require dose adjustments or monitoring.

Food Interactions

  • There are no specific food restrictions with Sitagliptin 50mg.
  • A balanced diet supports the medicationโ€™s blood sugar-lowering effects.

Sitagliptin 50mg Contraindications

This medication is not suitable for:

  • Individuals allergic to Sitagliptin or any of its components.
  • Patients with type 1 diabetes or diabetic ketoacidosis, as Sitagliptin is not indicated for these conditions.
  • Individuals with a history of pancreatitis unless advised by a healthcare provider.

Precautions and Warnings

  • Inform your doctor if you have a history of kidney issues, as Sitagliptin 50mg may require adjustments based on renal function.
  • Monitor for symptoms of pancreatitis, such as severe abdominal pain or persistent nausea.
  • Pregnant or breastfeeding women should consult their doctor before using this medication.
  • Regular monitoring of blood sugar levels is essential to evaluate the medicationโ€™s effectiveness.

Storage

  • Store Sitagliptin 50mg tablets at room temperature, away from heat, moisture, and direct sunlight.
  • Keep the medication in its original packaging and out of reach of children and pets.
  • Dispose of unused or expired tablets responsibly, following local disposal guidelines.

Safety Information

  • Use Sitagliptin 50mg only as directed by your healthcare provider.
  • Do not adjust the dosage or stop taking the medication without consulting your doctor.
  • Report any unusual symptoms, such as signs of pancreatitis or severe allergic reactions, to your healthcare provider immediately.
Quantity 112, 28, 56, 84
Manufacturer MSD Pharmaceuticals
Indian Brand Januvia 50mg
US Brand Name Januvia, Sitagliptin
Generic Name Sitagliptin
Dosage 50mg
Drug Type Tablets

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