Quinine 300mg Uses

Quinine 300mg is prescribed for:

  • Malaria Treatment: Specifically for uncomplicated cases of malaria caused by Plasmodium falciparum, often in combination with other antimalarial drugs.
  • Nocturnal Leg Cramps (Off-Label): May be used to alleviate persistent leg cramps in some individuals under medical supervision.

This medication is vital in regions with chloroquine-resistant malaria and is part of combination therapies to enhance treatment effectiveness.

How Does Quinine 300mg Work?

Quinine targets malaria parasites in red blood cells by:

  • Disrupting Parasite Metabolism: Inhibits the parasite’s ability to break down hemoglobin, leading to toxic buildup and parasite death.
  • Preventing Replication: Stops the growth and reproduction of the malaria parasite, effectively clearing the infection.

This action makes Quinine 300mg highly effective in eliminating malaria parasites and relieving symptoms.

How to Use Quinine 300mg

  1. Dosage: Take Quinine 300mg exactly as prescribed by your doctor. The dosage depends on the severity of the infection and may be part of a combination therapy.
  2. Administration: Swallow the tablet whole with water. It is best taken after a meal to minimize stomach upset.
  3. Timing: Typically taken every 8 hours for 3 to 7 days for malaria treatment.
  4. Adherence: Complete the full course of treatment to ensure the infection is fully eradicated and to prevent resistance.

Side Effects

Common side effects of Quinine 300mg include:

  • Nausea or vomiting
  • Stomach pain or diarrhea
  • Headache or dizziness
  • Tinnitus (ringing in the ears)
  • Blurred vision

Rare but severe side effects, such as low blood sugar, irregular heartbeat, or severe allergic reactions, require immediate medical attention. Discontinue use and consult your doctor if you experience unusual symptoms.

Drug Interactions

Quinine 300mg may interact with other medications. Inform your doctor if you are taking:

  • Antacids containing aluminum or magnesium
  • Blood thinners (e.g., warfarin)
  • Antiarrhythmics or medications affecting heart rhythm
  • Antidepressants or antianxiety drugs
  • Other antimalarial medications

Food Interactions

  • Meals: Quinine should be taken after food to reduce stomach irritation.
  • Grapefruit: Avoid grapefruit and grapefruit juice, as they may increase the risk of side effects by interfering with the medication’s metabolism.
  • Alcohol: Limit alcohol intake, as it may exacerbate side effects like dizziness or nausea.

Contraindications

Quinine 300mg is contraindicated in individuals who:

  • Are allergic to Quinine or related compounds
  • Have a history of blackwater fever or hemolytic anemia
  • Have conditions such as tinnitus or optic neuritis
  • Are pregnant (unless advised by a doctor) due to potential risks to the fetus

Precautions and Warnings

  • Pregnancy and Breastfeeding: Use Quinine 300mg during pregnancy only if recommended by your doctor. It may pass into breast milk, so consult your doctor before breastfeeding.
  • Heart Conditions: Regular monitoring is necessary for individuals with a history of heart problems or arrhythmias.
  • Blood Sugar Levels: Quinine may cause hypoglycemia (low blood sugar), particularly in pregnant women and those with diabetes.

Safety Information

  • Monitoring: Regular follow-ups may be needed to monitor response to treatment and check for potential side effects.
  • Medication Compliance: Complete the entire prescribed course to prevent the recurrence of malaria or resistance.
  • Travel Considerations: If traveling to a malaria-prone area, discuss preventive measures with your doctor.

Storage

  • Store Quinine 300mg at room temperature, away from heat, moisture, and direct sunlight.
  • Keep out of reach of children and pets.
  • Dispose of unused or expired medication responsibly.
Quantity 100, 150, 200, 50
Manufacturer Johnlee Pharma
Indian Brand Quineen 300mg
US Brand Name Quinbisul, Quinine, Quinsul
Generic Name Quinine
Dosage 300mg
Drug Type Tablets
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