Uses of Nifedipine Retard 20mg

Nifedipine Retard 20mg is used to treat high blood pressure (hypertension) by lowering blood pressure and reducing the risk of cardiovascular complications. It alleviates chest pain (angina) by improving blood flow to the heart muscle and reducing its oxygen demand. It may also be used to manage Raynaud’s phenomenon, a condition characterized by reduced blood flow to the extremities.

How Does Nifedipine Retard 20mg Work?

Nifedipine is a calcium channel blocker that inhibits the movement of calcium ions into smooth muscle cells of blood vessels and the heart. This action relaxes and dilates blood vessels, improving blood flow and reducing blood pressure. It also decreases the oxygen demand of the heart, alleviating symptoms of angina.

How to Use Nifedipine Retard 20mg

  • Dosage: Take Nifedipine Retard 20mg as directed by your healthcare provider, typically once or twice daily.
  • Administration: Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this may affect its controlled-release properties.
  • Timing: Take the medication at the same time each day to maintain consistent blood levels.
  • Missed Dose: If you miss a dose, take it as soon as you remember unless it is close to the next scheduled dose. Do not double the dose to make up for a missed one.

Side Effects

Common side effects of Nifedipine Retard 20mg include headache, flushing, dizziness, nausea, and swelling in the ankles or feet (peripheral edema). Rare but serious side effects include severe allergic reactions such as rash, swelling, or difficulty breathing, unusually fast or irregular heartbeat, chest pain that worsens, and signs of low blood pressure such as fainting or extreme dizziness. Seek immediate medical attention if you experience severe or persistent side effects.

Drug Interactions

Nifedipine Retard 20mg may interact with:

  • Other antihypertensive medications, which may enhance blood pressure-lowering effects.
  • Grapefruit or grapefruit juice, which can increase Nifedipine levels in the blood and amplify side effects.
  • Medications for heart conditions (e.g., Beta-blockers), which may require close monitoring.
  • CYP3A4 inhibitors (e.g., Ketoconazole, Erythromycin), which may increase the concentration of Nifedipine.
    Always inform your healthcare provider about all medications, supplements, and herbal products you are using.

Food Interactions

Avoid consuming grapefruit or grapefruit juice while taking Nifedipine, as it may interfere with the medication’s metabolism and increase the risk of side effects. Take the medication with or without food, as directed by your healthcare provider.

Contraindications

Nifedipine Retard 20mg is contraindicated in individuals with known hypersensitivity to Nifedipine or any other ingredients in the formulation, severe hypotension (low blood pressure), cardiogenic shock, or advanced aortic stenosis. Your healthcare provider will evaluate your medical history to ensure this medication is safe for you.

Precautions and Warnings

Regular monitoring of blood pressure is recommended to ensure the medication’s effectiveness. Use with caution in individuals with heart conditions, as it may affect heart rate or function. Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding, as the safety of Nifedipine in these populations requires evaluation. Do not abruptly stop taking Nifedipine without consulting your doctor, as this may worsen symptoms.

Safety Information

Seek immediate medical attention if you experience symptoms of severe allergic reactions, unusually fast or irregular heartbeat, or chest pain that worsens. Overdose symptoms may include severe dizziness, fainting, or difficulty breathing. Contact a healthcare provider or poison control center immediately if overdose occurs.

Storage

Store Nifedipine Retard 20mg tablets at room temperature, between 20–25°C (68–77°F). Keep the medication in a dry place, away from direct sunlight and excessive moisture. Avoid storing it in bathrooms. Ensure the medication is out of reach of children and pets. Dispose of unused or expired tablets responsibly, following local waste disposal guidelines.

Quantity 100, 200, 300, 400
Manufacturer J.B. Chemicals
Indian Brand Nicardia Retard 20mg
US Brand Name Nifedipine-Retard
Generic Name Nifedipine-Retard
Dosage 20mg
Drug Type Tablets
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