Naproxen 500mg Uses

Naproxen 500mg is indicated for:

  • Relief of symptoms of rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.
  • Managing acute pain and menstrual pain.
  • Treating tendonitis, bursitis, and other inflammatory conditions.
  • Controlling pain and inflammation resulting from gout attacks.

How Does Naproxen 500mg Work

Naproxen works by inhibiting cyclooxygenase (COX-1 and COX-2), essential enzymes in the prostaglandin synthesis pathway, which are responsible for inflammation, pain, and fever. By blocking these enzymes, naproxen effectively reduces the levels of prostaglandins, alleviating inflammation and pain.

How to Use Naproxen 500mg

  • Take Naproxen 500mg tablets orally with a full glass of water.
  • To prevent stomach upset, it is advisable to take this medication with food, milk, or an antacid.
  • Follow your healthcare provider’s instructions carefully regarding dosage and duration of treatment.
  • Do not crush, chew, or break the tablet. Swallow it whole.

Side Effects

Common side effects of Naproxen 500mg include:

  • Stomach upset
  • Nausea
  • Heartburn
  • Headache
  • Drowsiness
  • Dizziness Serious side effects can include high blood pressure, heart attack, stroke, stomach or intestinal bleeding, and kidney problems. Seek immediate medical attention if you experience symptoms like chest pain, slurred speech, and severe abdominal pain.

Drug Interactions

Naproxen can interact with several other medications, including:

  • Other NSAIDs
  • Blood thinners (e.g., warfarin)
  • Certain antidepressants (SSRIs and SNRIs)
  • Diuretics
  • ACE inhibitors Always inform your healthcare provider about all the medications you are taking to prevent potential harmful interactions.

Contraindications

Avoid using Naproxen 500mg if you:

  • Have experienced allergic reactions to naproxen or other NSAIDs.
  • Have a history of heart disease or stroke.
  • Are in the late stages of pregnancy, especially after 20 weeks.

Precautions and Warnings

  • Naproxen may increase the risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke, which can be fatal. This risk may increase with duration of use.
  • Patients with existing heart disease or risk factors for such disease may be at greater risk.
  • Naproxen is associated with an increased risk of serious gastrointestinal adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal.

Storage

Store at room temperature away from moisture and heat. Do not store in the bathroom. Keep all medications out of reach of children and pets.

Safety Information

Naproxen 500mg should be used under medical supervision with frequent check-ups to monitor its effects. Patients should not exceed the prescribed dose or duration of treatment to avoid increased risk of side effects.

Quantity 180, 270, 360, 90
Manufacturer RPG Life Science
Indian Brand Naprosyn 500mg
US Brand Name Aleve, Anaprox, Naprelan, Naprogesic, Naprosyn, Naproxen, Nurolasts, Proxen, Synflex
Generic Name Naproxen
Dosage 500mg
Drug Type Tablets
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