Naproxen 275mg

Uses of Naproxen 275mg

Naproxen 275mg is used to relieve pain and inflammation associated with conditions such as arthritis (osteoarthritis, rheumatoid arthritis), gout, and ankylosing spondylitis. It alleviates menstrual cramps (dysmenorrhea), reduces acute pain from injuries such as sprains and strains, and manages mild to moderate pain from other causes, including headaches and dental pain.

How Does Naproxen 275mg Work?

Naproxen works by inhibiting the production of prostaglandins, chemicals responsible for pain, inflammation, and fever. It blocks the action of cyclooxygenase (COX) enzymes, which are involved in prostaglandin synthesis. This action helps reduce swelling, alleviate pain, and improve joint mobility.

How to Use Naproxen 275mg

Take Naproxen 275mg as directed by your healthcare provider, usually every 6 to 12 hours as needed for pain relief. Swallow the tablet whole with a full glass of water. It can be taken with food or milk to minimize stomach upset. Do not lie down for at least 10 minutes after taking the medication. If you miss a dose, take it as soon as you remember. If it is close to your next dose, skip the missed dose. Do not double the dose to make up for a missed one.

Side Effects

Common side effects of Naproxen 275mg include stomach pain, nausea, heartburn, dizziness, and headache. Rare but serious side effects include severe allergic reactions such as rash, swelling, or difficulty breathing, gastrointestinal bleeding or ulcers, signs of kidney problems (e.g., changes in urine output), and symptoms of a heart attack or stroke (e.g., chest pain, shortness of breath). Seek immediate medical attention if you experience severe or persistent side effects.

Drug Interactions

Naproxen 275mg may interact with:

• Other NSAIDs (e.g., Ibuprofen, Aspirin), increasing the risk of gastrointestinal bleeding.
• Blood thinners (e.g., Warfarin), which may enhance the risk of bleeding.
• ACE inhibitors or diuretics, which may reduce their effectiveness.
• Lithium, as Naproxen can increase lithium levels in the blood.
• Methotrexate, which may increase the risk of toxicity.
  Always inform your healthcare provider about all medications, supplements, and herbal products you are using.

Food Interactions

Take Naproxen with food, milk, or an antacid to reduce stomach irritation. Avoid excessive alcohol consumption, as it may increase the risk of stomach bleeding.

Contraindications

Naproxen 275mg is contraindicated in individuals with a history of allergic reactions to NSAIDs, such as Aspirin, active gastrointestinal bleeding or ulcers, severe kidney or liver disease, or recent heart surgery (coronary artery bypass graft – CABG). Your healthcare provider will evaluate your medical history to ensure this medication is safe for you.

Precautions and Warnings

Use Naproxen 275mg with caution if you have a history of stomach or intestinal problems, cardiovascular disease, or high blood pressure. Regular monitoring of kidney and liver function is recommended for individuals on long-term NSAID therapy. Avoid using this medication during the last trimester of pregnancy, as it may harm the fetus. Consult your healthcare provider before using Naproxen if you are breastfeeding.

Safety Information

Seek immediate medical attention if you experience symptoms of gastrointestinal bleeding, such as black or tarry stools, severe abdominal pain, or blood in vomit. Overdose symptoms may include severe drowsiness, nausea, vomiting, or difficulty breathing. Contact a healthcare provider or poison control center immediately if overdose occurs.

Storage

Store Naproxen 275mg tablets at room temperature, between 20–25°C (68–77°F). Keep the medication in a dry place, away from direct sunlight and excessive moisture. Avoid storing it in bathrooms. Ensure the medication is out of reach of children and pets. Dispose of unused or expired tablets responsibly, following local waste disposal guidelines.