Mirabegron 25mg

Uses of Mirabegron 25mg

Mirabegron 25mg is used to treat symptoms of overactive bladder (OAB), including urinary urgency, frequency, and incontinence. It may also be used in combination with other medications for bladder control in individuals with persistent symptoms.

How Does Mirabegron 25mg Work?

Mirabegron activates beta-3 adrenergic receptors in the bladder’s detrusor muscle. This activation relaxes the bladder wall, increasing its capacity and reducing the urgency and frequency of urination. By targeting the bladder muscle directly, Mirabegron effectively improves bladder control and reduces the impact of OAB symptoms.

How to Use Mirabegron 25mg

Take Mirabegron 25mg as prescribed by your healthcare provider, typically once daily. Swallow the tablet whole with water; do not crush, chew, or split it, as this may interfere with its controlled release. It can be taken with or without food. If you miss a dose, take it as soon as you remember unless it is close to your next scheduled dose. Do not double the dose to make up for a missed one. Regular use as directed is essential for optimal results.

Side Effects

Common side effects of Mirabegron 25mg include headache, dry mouth, dizziness, constipation, and increased blood pressure. Rare but serious side effects include severe allergic reactions such as rash, swelling, or difficulty breathing, urinary retention or difficulty urinating, and irregular heartbeat or chest pain. Seek immediate medical attention if you experience severe or persistent side effects.

Drug Interactions

Mirabegron 25mg may interact with:

• Beta-blockers or medications affecting heart rhythm, as it may alter their effects.
• Anticholinergic medications, which may enhance urinary retention.
• Blood pressure medications, as Mirabegron can increase blood pressure.
• CYP2D6 substrates (e.g., Metoprolol, Desipramine), as Mirabegron may increase their blood levels.
  Always inform your healthcare provider about all medications, supplements, and herbal products you are using.

Food Interactions

Mirabegron 25mg can be taken with or without food. Avoid excessive caffeine intake, as it may exacerbate bladder symptoms such as urgency and frequency.

Contraindications

Mirabegron 25mg is contraindicated in individuals with severe uncontrolled hypertension, known hypersensitivity to Mirabegron or any of its ingredients, and severe liver or kidney impairment without appropriate dosage adjustment. Your healthcare provider will evaluate your medical history to ensure this medication is safe for you.

Precautions and Warnings

Regular monitoring of blood pressure is recommended during treatment, as Mirabegron can cause or exacerbate hypertension. Use with caution in individuals with a history of bladder obstruction or difficulty urinating. Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding, as the safety of Mirabegron in these populations has not been fully established. Contact your doctor immediately if you experience difficulty urinating or symptoms of urinary retention.

Safety Information

Seek immediate medical attention if you experience symptoms of severe allergic reactions, such as rash, swelling, or difficulty breathing, or unusual side effects like irregular heartbeat or chest pain. Overdose symptoms may include severe dizziness, fainting, or urinary retention. Contact a healthcare provider or poison control center immediately if overdose occurs.

Storage

Store Mirabegron 25mg tablets at room temperature, between 20–25°C (68–77°F). Keep the medication in a dry place, away from direct sunlight and excessive moisture. Avoid storing it in bathrooms. Ensure the medication is out of reach of children and pets. Dispose of unused or expired tablets responsibly, following local waste disposal guidelines.