Indomethacin 75mg SR Capsules

Uses of Indomethacin 75mg SR Capsules

Indomethacin 75mg SR is used for:

• Arthritis: Provides relief from pain, stiffness, and inflammation caused by osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.
• Acute Gout: Reduces pain and inflammation during acute gout attacks.
• Bursitis and Tendonitis: Eases inflammation and pain in the joints and tendons.
• Mild to Moderate Pain: Manages pain from injuries or post-surgical conditions.

This medication is effective in reducing symptoms but does not cure the underlying conditions.

How Does Indomethacin 75mg SR Work?

Indomethacin belongs to the NSAID class of drugs and works by:

• Inhibiting the production of prostaglandins, chemicals in the body responsible for pain and inflammation.
• Reducing swelling, redness, and discomfort in affected areas.

The sustained-release formulation ensures consistent levels of medication in the body, providing prolonged relief from symptoms.

How to Use Indomethacin 75mg SR Capsules

• Dosage: The typical dose is one capsule (75mg) once or twice daily, depending on your condition and your doctor’s recommendation.
• Administration: Swallow the capsule whole with a full glass of water. Do not crush, chew, or open the capsule.
• Timing: Take the medication with food or milk to minimize stomach irritation.
• Missed Dose: If you miss a dose, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose. Avoid doubling the dose to make up for a missed one.

Always follow your healthcare provider’s instructions for safe and effective use.

Side Effects

Common side effects of Indomethacin 75mg SR Capsules include:

• Nausea or vomiting
• Heartburn or stomach pain
• Headache or dizziness
• Diarrhea or constipation

Serious but less common side effects include:

• Stomach ulcers or bleeding, with symptoms such as black or tarry stools
• High blood pressure
• Kidney or liver dysfunction, indicated by unusual fatigue, yellowing of the skin or eyes, or dark urine
• Severe allergic reactions, such as rash, swelling, or difficulty breathing

Seek immediate medical attention if you experience severe or persistent side effects.

Drug Interactions

Indomethacin may interact with other medications, leading to increased side effects or reduced effectiveness. Common interactions include:

• Anticoagulants (e.g., Warfarin): May increase the risk of bleeding.
• Diuretics: Can reduce the effectiveness of diuretics and increase the risk of kidney problems.
• ACE Inhibitors or ARBs (e.g., Lisinopril, Losartan): May decrease the effectiveness of these medications and worsen kidney function.
• Corticosteroids: May increase the risk of gastrointestinal side effects.
• SSRIs or SNRIs (e.g., Fluoxetine): Can increase the risk of bleeding.

Inform your healthcare provider about all medications, supplements, and herbal products you are taking.

Food Interactions

Indomethacin is best taken with food or milk to minimize the risk of stomach irritation. Avoid:

• Alcohol: Can increase the risk of stomach ulcers and bleeding.
• Caffeine: May exacerbate gastrointestinal discomfort when consumed in large amounts.

Discuss any dietary considerations with your healthcare provider to ensure safe use.

Contraindications

Indomethacin 75mg SR Capsules are contraindicated in the following cases:

• Known allergy to Indomethacin, other NSAIDs, or any component of the capsule.
• History of asthma or allergic reactions triggered by NSAIDs.
• Active or recent gastrointestinal bleeding or ulcer.
• Severe liver or kidney impairment.
• Pregnancy, especially during the third trimester, or breastfeeding.

Your doctor will evaluate your medical history to determine if this medication is suitable for you.

Precautions and Warnings

• Cardiovascular Risk: Prolonged use of NSAIDs may increase the risk of heart attack or stroke, especially in patients with pre-existing heart conditions.
• Gastrointestinal Risk: Indomethacin can cause stomach ulcers, bleeding, or perforation, particularly in older adults or those with a history of ulcers.
• Liver and Kidney Monitoring: Regular tests are recommended to monitor liver and kidney function during long-term use.
• Pregnancy and Breastfeeding: Avoid using Indomethacin during pregnancy or while breastfeeding unless directed by your doctor.
• Driving and Machinery: Avoid activities requiring alertness if you experience dizziness or drowsiness.

Safety Information

• Emergency Situations: Seek immediate medical attention if you experience severe stomach pain, difficulty breathing, or symptoms of an allergic reaction.
• Overdose: Symptoms of overdose include nausea, vomiting, severe headache, confusion, or seizures. Contact your healthcare provider or poison control center immediately if an overdose occurs.
• Regular Monitoring: Routine check-ups with your doctor are essential to monitor for potential side effects and adjust treatment as needed.

Storage

• Temperature: Store Indomethacin 75mg SR Capsules at room temperature, between 20–25°C (68–77°F).
• Moisture and Light: Keep the medication in a dry place, away from direct sunlight and excessive moisture. Avoid storing it in bathrooms.
• Safety: Keep the capsules out of reach of children and pets to prevent accidental ingestion.
• Disposal: Dispose of unused or expired capsules responsibly, following local waste disposal guidelines.