Etoricoxib 90mg

Etoricoxib 90mg is a medication belonging to the class of drugs known as selective COX-2 inhibitors, which are a subset of non-steroidal anti-inflammatory drugs (NSAIDs). This specific dosage is primarily used for the management of osteoarthritis, rheumatoid arthritis, and the treatment of acute gouty arthritis. By selectively inhibiting the cyclooxygenase-2 enzyme, Etoricoxib 90mg reduces inflammation and pain without causing as much of the gastrointestinal side effects associated with traditional NSAIDs. In patients with osteoarthritis, Etoricoxib 90mg helps to reduce joint pain and stiffness, improving daily functioning. For those suffering from rheumatoid arthritis, it not only alleviates pain and inflammation but also helps in reducing joint damage over time with regular use. In the case of acute gouty arthritis, Etoricoxib provides rapid relief from pain and inflammation associated with high uric acid levels and crystal deposition in joints.

Drug Interactions

Etoricoxib 90mg can interact with several other medications, potentially altering their effects or increasing the risk of adverse reactions. It is important to avoid combining Etoricoxib with other NSAIDs, including aspirin, as this can increase the risk of gastrointestinal bleeding. The drug may also enhance the anticoagulant effect of warfarin and other coumarin anticoagulants, necessitating close monitoring of blood coagulation parameters.

When taken with ACE inhibitors or angiotensin receptor blockers used for hypertension, Etoricoxib can reduce their effectiveness and further deteriorate kidney function. Additionally, patients should be cautious when combining this medication with selective serotonin reuptake inhibitors (SSRIs), as this can increase the risk of gastrointestinal bleeding.

Food Interactions

Etoricoxib 90mg can be taken with or without food; however, some patients find that taking the medication with food can help to minimize potential gastrointestinal discomfort. There are no specific foods that need to be avoided while on Etoricoxib, but it is generally advisable to maintain a balanced diet to support overall health.

Patients are advised to limit the intake of alcohol while taking Etoricoxib, as alcohol can increase the risk of stomach ulcers and gastrointestinal bleeding, particularly in those who are susceptible or using NSAIDs long-term.

Contraindications

Etoricoxib 90mg is contraindicated in patients with known hypersensitivity to Etoricoxib or any of its inactive components. It should not be administered to patients who have had episodes of bronchospasm, acute rhinitis, nasal polyps, angioneurotic edema, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.

This medication is also contraindicated in patients with active peptic ulceration or active gastrointestinal bleeding. Additionally, Etoricoxib should not be used by patients with severe hepatic dysfunction, severe heart failure, or those who have had a stroke or heart attack. Pregnant women, particularly in the third trimester, and breastfeeding mothers should avoid Etoricoxib due to potential risks to the fetus and infant.

Precautions and Warnings

Etoricoxib should be used with caution in patients with a history of gastrointestinal diseases as it can exacerbate conditions such as ulcers and GI bleeding. It should also be used cautiously in patients with renal impairment, as it may worsen kidney function, particularly in those who are dehydrated or elderly.

Patients with pre-existing heart conditions should use Etoricoxib only under close medical supervision, as it may increase the risk of hypertension and cardiac events. Regular monitoring of blood pressure is recommended for all patients on Etoricoxib, especially those with a history of hypertension.

Etoricoxib may cause dizziness or drowsiness; therefore, patients should exercise caution when driving or operating machinery until they know how the medication affects them.

Storage

Etoricoxib 90mg should be stored at room temperature, away from moisture and heat. Keep the medication in its original packaging to protect it from moisture, and ensure the container is tightly closed when not in use. Etoricoxib should be kept out of reach of children and pets to prevent accidental ingestion, which could be harmful.

Proper storage and handling of Etoricoxib 90mg are essential to maintain its effectiveness and minimize risks associated with accidental use. Always follow the storage instructions provided by the pharmacist or those found on the medication packaging, and consult a healthcare provider for any questions regarding its use or storage.