Esomeprazole 40mg with Sodium Bicarbonate Uses

This combination is prescribed for the treatment of gastroesophageal reflux disease (GERD), conditions involving excessive stomach acid like Zollinger-Ellison syndrome, and healing of erosive esophagitis. The addition of Sodium Bicarbonate buffers the stomach contents, providing faster relief from acidity and discomfort.

How Does Esomeprazole 40mg with Sodium Bicarbonate Work

Esomeprazole inhibits the proton pumps in the stomach cells that produce gastric acid, significantly reducing acid output. Sodium Bicarbonate acts as a buffer to immediately neutralize stomach acid, protecting the stomach lining and decreasing discomfort upon ingestion.

How to Use Esomeprazole 40mg with Sodium Bicarbonate

  • Take this medication at least one hour before meals, preferably in the morning.
  • Swallow the capsules whole with water; do not crush, chew, or split them.
  • Follow your healthcare provider’s directions precisely regarding the duration of treatment, which typically ranges from 4 to 8 weeks.

Side Effects

Common side effects include:

  • Headache
  • Nausea
  • Diarrhea
  • Stomach pain
  • Gas or bloating

Serious side effects may include:

  • Severe allergic reactions
  • Kidney problems such as acute interstitial nephritis
  • Symptoms of low magnesium such as muscle spasms and irregular heartbeat

Drug Interactions

Potential interactions include:

  • Reduced effectiveness of Clopidogrel, important for patients with heart conditions.
  • Interaction with antiretrovirals and antifungals, affected by changes in stomach pH.
  • Increased risk of bleeding when taken with warfarin or similar anticoagulants.

Food Interactions

  • There are generally no specific food interactions, but it’s best to avoid foods that trigger reflux or are highly acidic, as they may worsen symptoms of GERD.

Esomeprazole 40mg with Sodium Bicarbonate Contraindications

Avoid using this medication if you:

  • Are allergic to Esomeprazole, other proton pump inhibitors, or bicarbonate salts.
  • Are taking HIV medications that include rilpivirine.

Precautions and Warnings

  • Long-term use may lead to mineral deficiencies (such as magnesium and calcium) and increase the risk of bone fractures.
  • Consult your doctor if you have a history of liver disease or osteoporosis.
  • Esomeprazole may mask the symptoms of gastric cancer; ongoing symptoms should be evaluated thoroughly.

Storage

  • Store at room temperature away from moisture and excessive heat.
  • Keep capsules in their original package to protect them from moisture.

Safety Information

  • This medication should only be used under the guidance of a healthcare professional.
  • Regular monitoring by your doctor is advised to check for effectiveness and side effects.
  • Do not share this medication with others, even if they have similar symptoms.
Quantity 120, 30, 60, 90
Manufacturer Torrent Pharmaceuticals Ltd
Indian Brand Nexpro Fast 40mg
US Brand Name Esomeprazole | Nexium
Generic Name Esomeprazole
Dosage 40mg
Drug Type Capsules
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