Enalapril-Hydrochlorothiazide 10mg-25mg

Enalapril-Hydrochlorothiazide 10mg-25mg is a combination medication primarily used for treating high blood pressure (hypertension). Enalapril belongs to a class of drugs known as ACE inhibitors, which work by relaxing blood vessels, thus lowering blood pressure. Hydrochlorothiazide is a thiazide diuretic (sometimes called a water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention. Together, these medications help reduce the risk of strokes and heart attacks by maintaining proper blood pressure levels.

In addition to hypertension, this combination may also be used for other conditions as determined by a healthcare provider. It is effective in helping to prevent complications of high blood pressure such as kidney problems and blindness.

Drug Interactions

Enalapril-Hydrochlorothiazide 10mg-25mg can interact with several other medications, which can significantly affect how it works or increase the risk of serious side effects. It’s important to discuss all medications you are currently taking with your doctor, including prescription drugs, over-the-counter products, and herbal supplements.

Some significant interactions include:

• NSAIDs (non-steroidal anti-inflammatory drugs): Medications like ibuprofen and naproxen can reduce the effectiveness of Enalapril-Hydrochlorothiazide and worsen kidney function.
• Lithium: Levels of lithium may be increased by hydrochlorothiazide, leading to an increased risk of lithium toxicity.
• Potassium supplements and potassium-sparing diuretics: These can increase potassium levels in your blood, possibly leading to dangerous heart irregularities when taken with this medication.

Always check with your healthcare provider before starting or stopping any medication.

Food Interactions

When taking Enalapril-Hydrochlorothiazide, certain food interactions should be considered to optimize the effectiveness of the treatment and reduce side effects:

• Salt substitutes and high-potassium foods: Since hydrochlorothiazide can cause potassium loss, high potassium diets or supplements should be used cautiously under medical advice.
• Alcohol: Drinking alcohol can increase certain side effects of hydrochlorothiazide and enalapril, such as dizziness and dehydration.
• Licorice: Eating large amounts of licorice can decrease the effectiveness of hydrochlorothiazide.

It’s advisable to maintain a balanced diet and drink plenty of water while on this medication unless otherwise directed by your doctor.

Contraindications

Enalapril-Hydrochlorothiazide 10mg-25mg is contraindicated in individuals who have:

• Hypersensitivity to enalapril, hydrochlorothiazide, or any other ACE inhibitor.
• History of angioedema related to previous ACE inhibitor treatment.
• Severe kidney impairment or anuria (non-production of urine).
• Severe liver impairment.

This medication is also not recommended during pregnancy, especially in the second and third trimesters, as it may cause harm to the fetus.

Precautions and Warnings

While taking Enalapril-Hydrochlorothiazide, certain precautions should be followed:

• Blood Pressure: Monitor blood pressure regularly to ensure that the desired effect is achieved.
• Electrolyte Imbalance: Hydrochlorothiazide can cause imbalances in electrolytes (such as potassium, sodium, magnesium). Regular blood tests may be required to monitor these levels.
• Kidney Function: Since enalapril can affect kidney function, kidney performance should be monitored during treatment.
• Pregnancy: As previously mentioned, use of this medication during pregnancy is discouraged due to the potential for harm to the unborn baby.

Patients should also be aware of symptoms like swelling, rapid weight gain, or shortness of breath, which should be reported to a healthcare provider immediately.

Storage

Enalapril-Hydrochlorothiazide 10mg-25mg should be stored at room temperature, away from moisture and heat. Keep the medication in its original packaging until ready to use, and keep out of reach of children and pets. Avoid storing this medication in areas where it could be exposed to excessive heat or moisture, such as bathrooms.

By following these guidelines and discussing your treatment with a healthcare provider, Enalapril-Hydrochlorothiazide 10mg-25mg can be an effective and safe option for managing hypertension.